Condition

MCI clinical trials and research

• 13Clinical trials
• 4Countries

Newest MCI clinical trials

All recruiting trials (13)

• See if cognitive impairment is common in older adults admitted for non-neurological rehab

  This study tests how often cognitive impairment appears in patients aged 45 and older who are in non-neurological rehab units after hospitalization.

  Recruiting at 3 sites Fondazione Don Carlo Gnocchi ETS · Florence, FI and 2 other locations · NCT07731334

• PET imaging with [18F]Flortaucipir to visualize tau in Alzheimer's and MCI

  We will test whether a PET imaging agent called [18F]Flortaucipir is safe and helps show tau in the brains of Chinese adults with Alzheimer's disease or mild cognitive impairment.

  Recruiting Phase 1 Eli Radiopharma · Beijing, Beijing Municipality · NCT07580703

• Five-week Telehealth Cognitive Training for Mild Cognitive Impairment

  A five-week, at-home, telehealth program tests whether a shorter cognitive training works as well as the original eight-week version for people with mild cognitive impairment.

  Recruiting University of Florida · Gainesville, Florida · NCT07366346

• Digital platform for early detection of Alzheimer-related memory impairment

  The platform will be tested to see if combining EEG, eye-tracking, and blood flow sensors can detect early memory-related cognitive impairment in people aged 55–80.

  Recruiting IRCCS San Raffaele · Milan, Italy · NCT07272811

• Omics-based profiling to find disease mechanisms and biomarkers in Alzheimer’s, Parkinson’s, FTD, and related dementias

  This project will use advanced omics tests (genetics, gene expression, proteins, and metabolites) to try to find biological markers and disease mechanisms in people with Alzheimer’s, Parkinson’s, frontotemporal and young-onset dementias, or mild cognitive impairment.

  Recruiting Ospedale Policlinico San Martino · Genoa, Genoa · NCT07235111

• FACE Phase II: Facial-expression personalization for at-home cognitive training

  This project tests whether a facial-expression personalization system can track and adjust real-time engagement to improve adherence to home-based computerized cognitive training for older adults at risk for Alzheimer's disease.

  Recruiting Phase 1/2 Stanford University · Palo Alto, California · NCT07130669

• Imaging demyelination with [18F]3F4AP PET

  This test uses a PET tracer called [18F]3F4AP in adults with demyelinating conditions and in healthy volunteers to see how the tracer moves through the body.

  Recruiting Phase 1 Yale University · New Haven, Connecticut · NCT06999434

• Testing dimethyl fumarate for improving cognitive functions in Alzheimer's patients

  This study is testing if a medication called dimethyl fumarate can help improve memory and thinking skills in older adults with mild cognitive impairment and early-stage Alzheimer's disease.

  Recruiting Phase 2 Medical University of Lodz · Lodz, Łódź Voivodeship · NCT06850597

• Identifying brain and inflammation markers in older adults at risk of dementia

  This study is trying to find specific brain and inflammation signs in older adults with early memory problems to help identify those at risk for dementia and create better early treatments.

  Recruiting IRCCS Fondazione Stella Maris · Pisa · NCT06746909

• Improving attention and wellbeing in older adults using digital tools

  This study is testing how different digital tools can help older adults improve their attention and overall wellbeing, especially for those at risk of dementia.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06397469

• Effects of social isolation and interaction on dementia risk in people with subjective cognitive decline

  This study is trying to see how being socially isolated or interacting with others affects the risk of dementia in people who notice early signs of memory problems.

  Recruiting The First Affiliated Hospital with Nanjing Medical University · Nanjing, China, Jiangsu · NCT06335836

• Using brain stimulation to improve memory in older adults with mild cognitive impairment

  This study is testing if a special brain stimulation technique can help older adults with mild cognitive impairment improve their memory.

  Recruiting Indiana University · Durham, North Carolina · NCT05460468

• Observing cognitive impairment in older adults

  This study looks at older adults to see how mild cognitive impairment and dementia develop, hoping to find better ways to prevent and treat these conditions.

  Recruiting Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Guangzhou, Guangdong · NCT04360200

Related topics

Quick answers

How many MCI clinical trials are recruiting right now?

13, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 4 countries. The most sites are in United States (5 trials), Italy (4 trials), China (3 trials), Poland (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 2, Phase 2: 1, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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