Observing cognitive impairment in older adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on understanding mild cognitive impairment (MCI) and neurocognitive disorders such as Alzheimer's disease and vascular dementia in elderly populations. It aims to establish a prospective cohort to gather comprehensive epidemiological data and biological samples, which will aid in early prevention, diagnosis, and treatment of cognitive disorders. The study will utilize gene and brain imaging biomarkers to enhance the understanding of dementia pathogenesis and improve targeted interventions. By addressing the rising burden of dementia in China, the study seeks to provide valuable insights into this public health issue.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients over 50 years old.
2. Sign informed consent.
3. According to DSM-IV, the diagnostic standard of dementia was not met.
4. The clinical dementia rating (CDR) was 0.5.

Exclusion criteria:

1. Subjects with mental retardation.
2. Refuse to have blood sampling, imaging and other examinations.
3. Uncooperative subjects that have serious organic diseases, or have a history of mental illness, or have physical disability (including severe aphasia).
4. Contraindications of MR scanning.
5. Suffering from serious physical or mental illness.

Where it's running

• Sun Yat-sen Memorial Hospital, Sun Yat-sen University
  Guangzhou, Guangdong, China Recruiting

Study contacts

• Study coordinator: Yamei Tang
• Email: yameitang@hotmail.com
• Phone: +86-020-34070569

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.