Condition
Lower Extremity clinical trials and research
As of November 12, 2026, Find a Trial lists 5 Lower Extremity clinical trials that are recruiting, at sites in 8 countries (most in Turkey (Türkiye) (1), Australia (1), Germany (1)). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 5Clinical trials
- 8Countries
Newest Lower Extremity clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Bupivacaine plus lidocaine versus bupivacaine alone for ultrasound-guided popliteal sciatic nerve block | — | Erzurum | Recruiting | Apr 24, 2026 |
| Intrathecal dexmedetomidine plus fentanyl with bupivacaine for spinal anesthesia during above-knee amputation | — | Cairo | Recruiting | Dec 11, 2025 |
| Lower leg skin grafts after tumour removal: does negative pressure dressings help or not? | — | Malmö | Recruiting | Jun 27, 2025 |
| Photoacoustic imaging of blood vessels and oxygen in the lower leg and foot | — | Guangzhou, Guangdong | Recruiting | Aug 30, 2024 |
| Registry to evaluate the C-Brace System for lower extremity pareses | — | Harrison, Arkansas and 75 other locations | Recruiting | Nov 23, 2020 |
All recruiting trials (5)
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Bupivacaine plus lidocaine versus bupivacaine alone for ultrasound-guided popliteal sciatic nerve block
This trial will test whether adding lidocaine to bupivacaine gives faster numbness and longer-lasting pain relief for adults having below-knee (foot or ankle) surgery with an ultrasound-guided popliteal sciatic nerve block.
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Intrathecal dexmedetomidine plus fentanyl with bupivacaine for spinal anesthesia during above-knee amputation
This trial will test whether adding intrathecal dexmedetomidine to fentanyl and bupivacaine gives better and longer pain relief after above-knee amputation for adults with lower-limb sarcoma.
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Lower leg skin grafts after tumour removal: does negative pressure dressings help or not?
This trial tests whether negative pressure wound therapy over split-thickness skin grafts on the lower leg reduces infection compared with traditional dressings in adults after skin tumour removal.
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Photoacoustic imaging of blood vessels and oxygen in the lower leg and foot
This observational project will try a non-contrast photoacoustic scan of the feet to see if it can show blood vessel structure and oxygen levels in people with and without lower extremity artery disease.
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Registry to evaluate the C-Brace System for lower extremity pareses
This study is testing how well the C-Brace System works for people with weak legs to see if it helps them move better and improve their quality of life.
Related topics
Quick answers
How many Lower Extremity clinical trials are recruiting right now?
5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 8 countries. The most sites are in Turkey (Türkiye) (1 trial), Australia (1 trial), Germany (1 trial), Japan (1 trial), United States (1 trial). Each study page lists its sites and which ones are recruiting.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.