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Registry to evaluate the C-Brace System for lower extremity pareses

A Prospective Registry of Patients Fitted With a Microprocessor-controlled Knee Ankle Foot Orthosis

Otto Bock Healthcare Products GmbH · NCT04640584

This study is testing how well the C-Brace System works for people with weak legs to see if it helps them move better and improve their quality of life.

Quick facts

Study typeObservational
Enrollment250 (estimated)
SexAll
SponsorOtto Bock Healthcare Products GmbH (industry)
Locations76 sites (Harrison, Arkansas and 75 other locations)
Trial IDNCT04640584 on ClinicalTrials.gov

What this trial studies

The C-Brace Prospective Registry aims to collect safety and effectiveness data for the C-Brace System in patients with lower extremity pareses. Participants who have been fitted for the C-Brace will be enrolled and followed according to standard care protocols, which include baseline evaluations and follow-up assessments at 6, 12, 24, and 36 months. This observational study will gather both baseline and follow-up data to better understand the impact of the C-Brace on patient mobility and quality of life.

Who should consider this trial

Good fit: Ideal candidates are patients who have been evaluated, tested with the Trial Tool, and casted for a C-Brace fitting.

Not a fit: Patients who are geographically inaccessible or have not been casted for a C-Brace fitting may not benefit from this study.

Why it matters

Potential benefit: If successful, this registry could provide valuable insights into the effectiveness of the C-Brace, potentially improving mobility and quality of life for patients with lower extremity pareses.

How similar studies have performed: While this registry approach is not novel, it builds on existing methodologies to evaluate assistive devices, and similar studies have shown success in gathering meaningful data on patient outcomes.

Eligibility criteria

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* Patient has been evaluated and successfully tested with the Trial Tool, and has been casted for a C-Brace.
* Patient is able to communicate, provide feedback, understand and follow instructions during the course of the registry.
* Patient is willing to provide informed consent.

Exclusion Criteria:

* Patient is geographically inaccessible to comply and participate in the registry.
* Patient has not been casted for a C-Brace fitting.

Where this trial is running

Harrison, Arkansas and 75 other locations

+26 more sites — see ClinicalTrials.gov for the full list.

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Pareses, Lower Extremity

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.