Condition

Invasive Breast Carcinoma clinical trials and research

• 19Clinical trials
• 7Countries

Newest Invasive Breast Carcinoma clinical trials

All recruiting trials (19)

• Circulating microRNA changes to predict neoadjuvant chemotherapy response in breast cancer.

  This will test whether changes in blood microRNA levels before and after chemotherapy can help predict who will have a strong tumor response to neoadjuvant chemotherapy for breast cancer.

  Recruiting Atlas University · Istanbul · NCT07289282

• Imlunestrant and Abemaciclib for ER+ Breast Cancer with Minimal Residual Disease

  This Phase 2 trial tests whether taking imlunestrant and abemaciclib together can help people with ER-positive breast cancer who still have detectable cancer after initial treatment.

  Recruiting Phase 2 Jonsson Comprehensive Cancer Center · Los Angeles, California · NCT07191717

• Safety of combining pidnarulex (CX-5461) with trastuzumab deruxtecan for HER2-positive, HER2-low/ultralow breast and other HER2-expressing solid tumors

  This trial tests whether adding pidnarulex to trastuzumab deruxtecan is safe and finds the best dose for adults with HER2-positive, HER2-low/ultralow, or other HER2-expressing advanced or metastatic breast and solid tumors.

  Recruiting at 2 sites Phase 1 National Cancer Institute (NCI) · Boston, Massachusetts and 1 other locations · NCT07137416

• Sentinel lymph node biopsy after neoadjuvant chemotherapy for inflammatory breast cancer

  This trial will test whether sentinel lymph node biopsy after preoperative chemotherapy is feasible and safe for people with inflammatory breast cancer who initially had extensive lymph node involvement.

  Recruiting European Institute of Oncology · Milan · NCT07080944

• Using metformin to treat insulin resistance in women with early-stage breast cancer after chemotherapy

  This study is testing if metformin can help women with early-stage breast cancer who have finished chemotherapy and are struggling with insulin resistance to improve their health.

  Recruiting Phase 3 City of Hope Medical Center · Duarte, California and 2 other locations · NCT06763328

• Single-port robotic breast-conserving surgery through the armpit

  This project will try single-port robotic breast-conserving surgery through the armpit in adults (18–65) with early invasive breast cancer who are candidates for breast conservation and compare it with traditional open breast-conserving surgery.

  Recruiting Daping Hospital and the Research Institute of Surgery of the Third Military Medical University · Chongqing, Chongqing Municipality and 1 other locations · NCT06738654

• Biorepository for breast cancer survivors

  This study is collecting blood samples and health information from women who have survived early to moderate stage breast cancer to help with future research on survivorship.

  Recruiting University of Southern California · Los Angeles, California · NCT05786664

• Combining letrozole and simvastatin to treat hormone receptor positive breast cancer

  This study tests if combining letrozole with simvastatin can help shrink tumors in postmenopausal women with hormone receptor positive breast cancer better than using letrozole alone.

  Recruiting at 4 sites Early Phase 1 Emory University · Atlanta, Georgia and 3 other locations · NCT05464810

• Assessing immune changes in breast cancer patients after radiation therapy

  This study is testing how radiation therapy affects the immune system in breast cancer patients by looking at changes in immune cells and DNA damage before and after treatment.

  Recruiting M.D. Anderson Cancer Center · Houston, Texas · NCT05406232

• Collecting blood samples to evaluate tests for early cancer detection

  This study is collecting blood and tissue samples from people with and without cancer to see if new tests can help detect cancer earlier.

  Recruiting at 619 sites Alliance for Clinical Trials in Oncology · Anchorage, Alaska and 750 other locations · NCT05334069

• Time restricted eating for patients with HER2 negative breast cancer undergoing chemotherapy

  This study is testing if following a time-restricted eating schedule can help women with HER2 negative breast cancer feel better and respond better to chemotherapy.

  Recruiting at 5 sites Thomas Jefferson University · Cherry Hill, New Jersey and 4 other locations · NCT05327608

• Observing cancer recurrence using a blood test

  This study is testing a new blood test to see if it can help find out if cancer comes back in people who have been treated for early-stage solid tumors.

  Recruiting at 49 sites Guardant Health, Inc. · Birmingham, Alabama and 56 other locations · NCT05059444

• Caloric restriction combined with targeted radiation therapy for early stage breast cancer

  This study is testing if cutting calories while getting targeted radiation therapy can help reduce tumor size more in people with early stage breast cancer compared to just the radiation alone.

  Recruiting Thomas Jefferson University · Philadelphia, Pennsylvania · NCT04959474

• A vaccine using modified measles virus for treating metastatic breast cancer

  This study is testing a modified measles virus vaccine to see if it can safely help people with metastatic breast cancer by shrinking their tumors.

  Recruiting Phase 1 Mayo Clinic · Rochester, Minnesota · NCT04521764

• Impact of COVID-19 on financial costs for breast cancer surgery patients

  This study looks at how the COVID-19 pandemic has impacted the out-of-pocket costs and financial struggles of breast cancer patients undergoing surgery.

  Recruiting at 4 sites M.D. Anderson Cancer Center · Conroe, Texas and 3 other locations · NCT04169542

• Combining a personalized vaccine with chemotherapy and immunotherapy for metastatic triple-negative breast cancer

  This study is testing if adding a personalized vaccine to chemotherapy and immunotherapy can help people with metastatic triple-negative breast cancer feel better and improve their treatment outcomes.

  Recruiting at 24 sites Phase 2 National Cancer Institute (NCI) · Orange, California and 29 other locations · NCT03606967

• Eliminating surgery and radiation for certain breast cancer patients

  This study is testing if some breast cancer patients can skip surgery and just use radiation therapy after their initial treatment to see how it affects their cancer and quality of life.

  Recruiting at 6 sites M.D. Anderson Cancer Center · Gilbert, Arizona and 7 other locations · NCT02945579

• A tool to help patients decide on contralateral prophylactic mastectomy for breast cancer

  This study tests if an online tool can help women newly diagnosed with breast cancer make better choices about having a preventive mastectomy on the other breast.

  Recruiting M.D. Anderson Cancer Center · Houston, Texas · NCT02918474

• Collecting tissue and medical data from patients with inflammatory or invasive breast cancer

  This study is collecting blood, tissue, and other samples from patients with inflammatory or invasive breast cancer to help researchers learn more about the disease and improve treatments.

  Recruiting at 8 sites M.D. Anderson Cancer Center · Gilbert, Arizona and 9 other locations · NCT00477100

Related topics

Quick answers

How many Invasive Breast Carcinoma clinical trials are recruiting right now?

19, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in United States (16 trials), Italy (2 trials), France (1 trial), Germany (1 trial), Spain (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 2, Phase 2: 2, Early Phase 1: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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