A tool to help patients decide on contralateral prophylactic mastectomy for breast cancer

Decision Making Tool for Contralateral Prophylactic Mastectomy

NA · M.D. Anderson Cancer Center · NCT02918474

This study tests if an online tool can help women newly diagnosed with breast cancer make better choices about having a preventive mastectomy on the other breast.

Quick facts

PhaseNA
Study typeInterventional
Enrollment15 (estimated)
Ages18 Years and up
SexFemale
SponsorM.D. Anderson Cancer Center (other)
Locations1 site (Houston, Texas)
Trial IDNCT02918474 on ClinicalTrials.gov

What this trial studies

This trial evaluates the effectiveness of an online decision support tool designed to assist patients with newly diagnosed breast cancer in making informed choices about contralateral prophylactic mastectomy (CPM). The tool provides evidence-based information regarding the risk of contralateral breast cancer and the potential life expectancy benefits of undergoing CPM. Patients will use this tool during consultations with their breast cancer surgeon and will complete questionnaires before and after the consultation to assess its impact on their decision-making process.

Who should consider this trial

Good fit: Ideal candidates are patients newly diagnosed with ductal breast carcinoma in situ or stage I-III sporadic unilateral invasive breast cancer who can communicate in English.

Not a fit: Patients with a history of breast cancer, prior bilateral prophylactic mastectomy, or known genetic predispositions to breast cancer may not benefit from this study.

Why it matters

Potential benefit: If successful, this tool could empower patients to make more informed decisions regarding their surgical options, potentially improving their satisfaction and outcomes.

How similar studies have performed: Other studies have shown that decision support tools can significantly improve patient decision-making in cancer care, suggesting a positive outlook for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Newly diagnosed ductal breast carcinoma in situ (DCIS) or stage I-III sporadic unilateral invasive breast cancer
* Able to speak read or write English

Exclusion Criteria:

* Patients with previous breast cancer
* Prior history of bilateral prophylactic mastectomy
* Known to have a germline mutation that predisposes them to an increased risk of breast cancer (e.g. BRCA1/2) and/or they are considered at high risk for contralateral breast cancer on the basis of a strong family history of cancer

Where this trial is running

Houston, Texas

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIA Breast Cancer AJCC v8, Anatomic Stage IIB Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.