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Clinical trial Recruiting at 1 site Interventional Ages 18 and up Women only

Single-port robotic breast-conserving surgery through the armpit

Official title: Application of Single-Port Robot-Assisted Breast-Conserving Surgery Via Axillary Approach for Breast Cancer.

Run by Daping Hospital and the Research Institute of Surgery of the Third Military Medical University · NCT06738654 · Data updated 2026-11-12

This project will try single-port robotic breast-conserving surgery through the armpit in adults (18–65) with early invasive breast cancer who are candidates for breast conservation and compare it with traditional open breast-conserving surgery.

Quick facts

Study typeInterventional
Ages18 Years and up
SexWomen only
Enrollment64 (estimated)
SponsorDaping Hospital and the Research Institute of Surgery of the Third Military Medical University
Academic / other
Locations2 sites (Chongqing, Chongqing Municipality and 1 other locations)
StatusRecruiting
StartedDecember 31, 2024
Main results expectedDecember 30, 2027
Study endsDecember 31, 2027
Registry record updatedAugust 21, 2026
Trial IDNCT06738654 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18–65 with early-stage invasive breast cancer who are suitable candidates for breast-conserving surgery, have not had prior chest surgery or radiotherapy, and have no contraindications to anesthesia are the intended participants.

Probably not a fit

Patients with inflammatory breast cancer, extensive or multifocal disease that makes negative margins or an acceptable cosmetic result unlikely, diffuse malignant calcifications, positive margins that cannot be cleared by re-resection, prior chest surgery or radiotherapy, or those who refuse the procedure are unlikely to benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults who meet inclusion criteria will receive either single-port robot-assisted breast-conserving surgery via an axillary incision or conventional open breast-conserving surgery, with the surgical approach chosen based on patient financial considerations and equipment availability rather than random assignment. Preoperative imaging and clinical data are collected, and intraoperative metrics such as operating time, blood loss, and intraoperative events are recorded. Postoperative outcomes include complications, pain scores, pathological margins, length of hospital stay, and complication/mortality rates tracked at 28 and 90 days. The study compares safety, feasibility, perioperative recovery, and cosmetic-related outcomes between the two approaches.

Why it matters

Potential benefit: If successful, the single-port axillary robotic approach could reduce visible chest scarring and better preserve breast shape while matching or improving recovery and complication rates versus open surgery.

How similar studies have gone: Robotic and endoscopic approaches to breast-conserving and nipple-sparing procedures have been reported in small series with promising cosmetic and recovery results, but the single-port axillary robotic technique remains relatively novel and has limited comparative published data.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

1. The patient himself has very high requirements for beauty, and requires no scar on the chest;
2. No chest surgery and radiotherapy.
3. No contraindications to surgery and anesthesia.
4. Clinical I, stage of early breast cancer and the breast has an appropriate volume, can maintain a good breast shape after surgery.
5. Patients in the clinical period who meet the standard of breast conservation surgery after preoperative treatment.
6. Age: ≥18 years old.

Exclusion Criteria:

1. Inflammatory breast cancer.
2. The tumor is extensive and it's difficult to achieve negative margins or an ideal breast - conserving appearance.
3. Diffusely distributed malignant - characteristic calcifications.
4. The margin is positive after local extensive tumor resection, and a negative margin in pathological examination still can't be ensured after re - resection.
5. The patient refuses.

Where it's running

  • Army Medical Center
    Chongqing, Chongqing Municipality, China     Recruiting
  • Aramy medical center.
    Chongqing, Chongqing Municipality, China     Not yet recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.