Condition

Heart Failure NYHA Class III clinical trials and research

• 13Clinical trials
• 8Countries

Newest Heart Failure NYHA Class III clinical trials

All recruiting trials (13)

• Yoga-based cardiac rehabilitation for heart failure with reduced ejection fraction

  This trial tests whether a yoga-based rehabilitation program can help people with heart failure and reduced ejection fraction compared with an educational program.

  Recruiting at 12 sites Centre for Chronic Disease Control, India · Dharwad, Karnataka and 15 other locations · NCT07817589

• Using BaroStim and CardioMems to improve care for NYHA Class III heart failure

  This study will see if adding BaroStim after three months of CardioMems-guided medication optimization helps people with NYHA Class III heart failure and LVEF under 35%.

  Recruiting Phase 2/3 Northwell Health · Riverhead, New York · NCT07399587

• SmartSignalHF remote monitoring for people with implanted ICD or CRT‑D and heart failure

  This tests whether SmartSignalHF remote monitoring for people with implanted ICD or CRT‑D and chronic heart failure can reduce deaths and heart failure hospital visits over 12 months compared with standard remote monitoring.

  Recruiting Implicity · Paris · NCT07247032

• Barostim therapy to help heart failure patients stay well

  This study tests whether Barostim System-based baroreflex activation can reduce death and serious heart failure events in adults with moderate heart failure already on guideline-directed therapy.

  Recruiting at 20 sites CVRx, Inc. · Mobile, Alabama and 22 other locations · NCT07232030

• Home palliative care for heart failure patients in rural Appalachia

  This study tests a new home care program for families taking care of loved ones with advanced heart failure in rural Appalachia to see if it improves their quality of life and reduces stress over a year.

  Recruiting West Virginia University · Morgantown, West Virginia · NCT06791850

• Evaluating the Cordella Pulmonary Artery Sensor for Chronic Heart Failure

  This study is testing if a new device that monitors heart pressure at home can help people with chronic heart failure stay out of the hospital and live longer compared to just taking standard medications.

  Recruiting Endotronix, Inc. · Naperville, Illinois · NCT06783335

• Hybrid cardiac rehabilitation for heart failure patients

  This study is testing if a new combined approach to heart rehab that includes exercise, medical support, and education helps people with heart failure feel better and improve their fitness more than just supervised exercise alone.

  Recruiting at 4 sites Universidad de La Frontera · Santiago and 3 other locations · NCT06313684

• Evaluating the Cordella Pulmonary Artery Sensor System for Heart Failure

  This study is testing a new device that helps people with heart failure keep track of their heart health to see if it can improve their management of the condition.

  Recruiting at 44 sites Endotronix, Inc. · Phoenix, Arizona and 47 other locations · NCT05934487

• Using lab-grown heart cells to treat congenital heart disease

  This study is testing if using heart cells made from patients' own skin can safely help people with congenital heart disease feel better.

  Recruiting Phase 1 HeartWorks, Inc. · Rochester, Minnesota · NCT05647213

• Transplanting heart tissue to aid recovery after heart surgery

  This study is testing if using small pieces of heart tissue from patients' own hearts during surgery can help them heal better and improve heart function after dealing with heart disease and heart failure.

  Recruiting Hospital District of Helsinki and Uusimaa · Helsinki, Uusimaa · NCT05632432

• Improving well-being and health in heart failure patients

  This study is testing a new phone-based program that combines positive psychology and motivational support to see if it can help heart failure patients improve their health and well-being over six months.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT04829617

• Baduanjin exercise program for chronic heart failure patients

  This study tests whether a traditional Chinese exercise program can help people with chronic heart failure feel better and improve their overall health.

  Recruiting Guangdong Provincial Hospital of Traditional Chinese Medicine · Guangzhou, Guangdong · NCT03180320

• Surgical correction of tricuspid valve issues in patients receiving LVADs

  This study is testing whether fixing tricuspid valve problems during the placement of a heart pump can help people with severe heart failure feel better.

  Recruiting University of Washington · Seattle, Washington · NCT02537769

Related topics

Quick answers

How many Heart Failure NYHA Class III clinical trials are recruiting right now?

13, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in United States (8 trials), Belgium (1 trial), Ireland (1 trial), India (1 trial), Chile (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2/3: 1, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →