Hybrid cardiac rehabilitation for heart failure patients
Official title: Comprehensive Hybrid Cardiac Rehabilitation Trial to Assess Impact on Heart Failure Patients
Run by Universidad de La Frontera · NCT06313684 · Data updated 2026-11-12
This study is testing if a new combined approach to heart rehab that includes exercise, medical support, and education helps people with heart failure feel better and improve their fitness more than just supervised exercise alone.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 152 (estimated) |
| Sponsor | Universidad de La Frontera Academic / other |
| Locations | 4 sites (Santiago and 3 other locations) |
| Status | Recruiting |
| Started | April 1, 2024 |
| Main results expected | September 2026 |
| Study ends | March 2027 |
| Registry record updated | December 3, 2024 |
| Trial ID | NCT06313684 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults with heart failure classified as NYHA Class II or III who are stable and on optimal medical therapy.
✕Probably not a fit
Patients with severe comorbidities or those who have recently undergone cardiac procedures may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This trial evaluates the effectiveness of a comprehensive hybrid cardiac rehabilitation model compared to supervised exercise alone for patients with heart failure. It involves a multi-center, randomized clinical trial design with two parallel arms, where participants will receive either a comprehensive intervention including medical management, exercise, psychosocial support, and education, or standard supervised exercise. The study aims to assess improvements in cardiorespiratory fitness, functional capacity, and quality of life over time. Participants will transition from center-based to home-based rehabilitation in a structured manner.
Why it matters
Potential benefit: If successful, this approach could significantly improve the quality of life and functional capacity for heart failure patients.
How similar studies have gone: Other studies have shown promising results with hybrid rehabilitation approaches in similar populations, indicating potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients with HF of New York Heart Association functional class II or III. * Meets HF diagnostic criteria of Guidelines * On optimal tolerated medical therapy. * Deemed by the treating physician as stable for at least 1 month. * Able to attend the health center three times a week for the first month, and twice a week for the 2nd and 3rd months * Owns a mobile phone * Patient consents to participate in the study by signing an informed consent form. Exclusion Criteria: * Chronic kidney disease with glomerular filtration rate \< 20 mL/min. * Decompensated thyroid disease. * End-stage liver failure or Child-Pugh C. * Cardiac device or cardiac surgery in the previous month or planned in the next 3 months. * Patients with dyspnea predominantly of non-cardiac cause (e.g. COPD). * Atrial fibrillation with a heart rate greater than 90 beats per minute at rest. * Active neoplasm with life expectancy \<2 years. * Inclusion in another interventional study. * Explicit contraindications to performing exercise. * Comorbidities that preclude the patient from engaging in a CR program. * Musculoskeletal or neurological disease that precludes the patient from performing exercise.
Where it's running
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Complejo Hospitalario San José
Santiago, Chile Recruiting -
Hospital Clínico Universidad de Chile
Santiago, Chile Recruiting -
Hospital San Borja Arriarán
Santiago, Chile Recruiting -
Universidad de La Frontera
Temuco, Chile Recruiting
Study contacts
- Principal investigator: Pamela Seron, PhD — Universidad de La Frontera
- Study coordinator: Francisca Contreras
- Email: mariafrancisca.contreras@ufrontera.cl
- Phone: 56045 2325765
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Yoga-based cardiac rehabilitation for heart failure with reduced ejection fraction
This trial tests whether a yoga-based rehabilitation program can help people with heart failure and reduced ejection fraction compared with an educational program.
-
SmartSignalHF remote monitoring for people with implanted ICD or CRT‑D and heart failure
This tests whether SmartSignalHF remote monitoring for people with implanted ICD or CRT‑D and chronic heart failure can reduce deaths and heart failure hospital visits over 12 months compared with standard remote monitoring.
-
Barostim therapy to help heart failure patients stay well
This study tests whether Barostim System-based baroreflex activation can reduce death and serious heart failure events in adults with moderate heart failure already on guideline-directed therapy.
-
Evaluating the Cordella Pulmonary Artery Sensor System for Heart Failure
This study is testing a new device that helps people with heart failure keep track of their heart health to see if it can improve their management of the condition.
-
Transplanting heart tissue to aid recovery after heart surgery
This study is testing if using small pieces of heart tissue from patients' own hearts during surgery can help them heal better and improve heart function after dealing with heart disease and heart failure.
-
Improving well-being and health in heart failure patients
This study is testing a new phone-based program that combines positive psychology and motivational support to see if it can help heart failure patients improve their health and well-being over six months.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.