NIH-funded research R01 grant

Understanding how brain function affects grief in older adults

Official title: Emotion Regulation in Complicated Grief

Funded at Medical College of Wisconsin · NIH-10764217 · Data updated 2026-11-12

This study is looking at how the brain helps older adults manage their feelings after losing someone they love, to see if it can help predict who will heal from their grief and who might need more support.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMedical College of Wisconsin
NIH-funded
Lab location1 site (Milwaukee, United States)
Project startFebruary 15, 2020
Project endJanuary 31, 2026
Funding year2024
Award (this year)$482,808
NIH project number5R01MH122490-05
Project IDNIH-10764217 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are older adults who have recently experienced the death of a loved one and are exhibiting signs of acute grief.

Less likely to help

Patients who are not experiencing significant grief or who have not recently lost a loved one may not benefit from this research.

What this research studies

This research investigates how the brain regulates emotions in older adults experiencing complicated grief after the loss of a loved one. It aims to identify neurobiological markers that can predict whether individuals will recover from acute grief or develop prolonged grief disorder. By using neuroimaging techniques, the study will analyze brain network functions related to emotion regulation and their impact on grief trajectories. The goal is to enhance understanding of grief and improve therapeutic approaches for those struggling with intense grief.

Why it matters

Potential benefit: If successful, this research could lead to better identification and treatment strategies for older adults suffering from complicated grief.

How similar studies have gone: Previous research has shown promising results in understanding the neurobiological aspects of grief, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Medical College of Wisconsin
    Milwaukee, United States
    Active

Researchers

  • Principal investigator: Goveas, Joseph S — Medical College of Wisconsin
  • Study coordinator: Goveas, Joseph S

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.