NIH-funded research R01 grant

Long-lasting grief after losing a loved one in older adults

Official title: Death of a loved one: Prevalence, risk, and protective factors for prolonged grief disorder

Funded at Harvard University D/b/a Harvard School of Public Health · NIH-11303447 · Data updated 2026-11-12

Researchers are finding how common long-lasting grief is and what factors make it more or less likely for adults aged 65 and older.

More Grief research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionHarvard University D/b/a Harvard School of Public Health
NIH-funded
Lab location1 site (Boston, United States)
Project startJuly 12, 2024
Project endFebruary 28, 2029
Funding year2026
Award (this year)$814,052
NIH project number5R01MH137201-03
Project IDNIH-11303447 on NIH RePORTER

Who could benefit from this research

Could help

Adults aged 65 and older who have experienced the death of a close loved one are the most relevant candidates for this research.

Less likely to help

People under 65 or those who do not have persistent, impairing grief symptoms are unlikely to benefit directly from this project.

What this research studies

This project looks at data from three long-term studies that together include tens of thousands of older adults to find who meets the new diagnostic criteria for prolonged grief disorder. Using information already collected about health, relationships, and life events, the team will identify risk and protective factors that relate to lasting, disabling grief. The work focuses on older adults because they face high rates of bereavement and higher risk for prolonged grief. The goal is to pinpoint changeable factors that could help clinicians recognize, prevent, or better refer people with prolonged grief.

Why it matters

Potential benefit: If successful, this work could help doctors and caregivers spot older adults at risk for prolonged grief earlier and suggest targets for prevention or treatment.

How similar studies have gone: Smaller studies have found prolonged grief affects a minority of bereaved adults, but applying the new DSM-5-TR criteria across very large, long-running cohorts is a new and important step.

Where this research is happening

  • Harvard University D/b/a Harvard School of Public Health
    Boston, United States
    Active

Researchers

  • Principal investigator: Denckla, Christy Ann — Harvard University D/b/a Harvard School of Public Health
  • Study coordinator: Denckla, Christy Ann

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.