Long-lasting grief after losing a loved one in older adults

Death of a loved one: Prevalence, risk, and protective factors for prolonged grief disorder

NIH-funded research Harvard University D/b/a Harvard School of Public Health · NIH-11303447

Researchers are finding how common long-lasting grief is and what factors make it more or less likely for adults aged 65 and older.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionHarvard University D/b/a Harvard School of Public Health NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11303447 on NIH RePORTER

What this research studies

This project looks at data from three long-term studies that together include tens of thousands of older adults to find who meets the new diagnostic criteria for prolonged grief disorder. Using information already collected about health, relationships, and life events, the team will identify risk and protective factors that relate to lasting, disabling grief. The work focuses on older adults because they face high rates of bereavement and higher risk for prolonged grief. The goal is to pinpoint changeable factors that could help clinicians recognize, prevent, or better refer people with prolonged grief.

Who could benefit from this research

Good fit: Adults aged 65 and older who have experienced the death of a close loved one are the most relevant candidates for this research.

Not a fit: People under 65 or those who do not have persistent, impairing grief symptoms are unlikely to benefit directly from this project.

Why it matters

Potential benefit: If successful, this work could help doctors and caregivers spot older adults at risk for prolonged grief earlier and suggest targets for prevention or treatment.

How similar studies have performed: Smaller studies have found prolonged grief affects a minority of bereaved adults, but applying the new DSM-5-TR criteria across very large, long-running cohorts is a new and important step.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.