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ctDNA Monitoring clinical trials and research
As of November 12, 2026, Find a Trial lists 3 ctDNA Monitoring clinical trials that are recruiting, at sites in 2 countries (most in China (2), United States (1)). By phase: Phase 2 (2), Phase 1/2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 2Countries
Newest ctDNA Monitoring clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| CDK4/6 inhibitors with endocrine therapy before surgery for HR+/HER2- high-risk early breast cancer | Phase 2 | Beijing, Beijing Municipality | Recruiting | Jan 26, 2026 |
| ctDNA-guided reduction of chemotherapy using dalpiciclib plus endocrine therapy in high-risk HR+/HER2- early breast cancer | Phase 2 | Beijing, Beijing Municipality | Recruiting | May 14, 2025 |
| Platform program for evaluating treatments in metastatic HER2-positive breast cancer | Phase 1/2 | Birmingham, Alabama and 9 other locations | Recruiting | May 22, 2023 |
All recruiting trials (3)
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CDK4/6 inhibitors with endocrine therapy before surgery for HR+/HER2- high-risk early breast cancer
This study tests whether adding a CDK4/6 inhibitor to endocrine therapy before surgery can help guide safer de-escalation of chemotherapy using ctDNA as a marker.
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ctDNA-guided reduction of chemotherapy using dalpiciclib plus endocrine therapy in high-risk HR+/HER2- early breast cancer
This trial tests whether giving the CDK4/6 drug dalpiciclib with endocrine therapy and using ctDNA results can let some women with early high-risk HR+/HER2- breast cancer skip or reduce chemotherapy.
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Platform program for evaluating treatments in metastatic HER2-positive breast cancer
This study is testing different new treatments for people with advanced HER2-positive breast cancer to see which ones work best before moving them to larger trials.
Related topics
Quick answers
How many ctDNA Monitoring clinical trials are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in China (2 trials), United States (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 2, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.