Condition
HER-2 Protein Overexpression clinical trials and research
As of November 12, 2026, Find a Trial lists 3 HER-2 Protein Overexpression clinical trials that are recruiting, at sites in 4 countries (most in United States (3), Georgia (1), South Korea (1)). By phase: Phase 1 (1), Phase 1/2 (1), Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 4Countries
Newest HER-2 Protein Overexpression clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Evaluating zanidatamab for HER2-expressing tumors | Phase 2 | Prescott, Arizona and 41 other locations | Recruiting | Nov 19, 2024 |
| Platform program for evaluating treatments in metastatic HER2-positive breast cancer | Phase 1/2 | Birmingham, Alabama and 9 other locations | Recruiting | May 22, 2023 |
| Using HER2 CAR T cells with checkpoint inhibitors for advanced sarcoma | Phase 1 | Houston, Texas | Recruiting | Aug 6, 2021 |
All recruiting trials (3)
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Evaluating zanidatamab for HER2-expressing tumors
This study is testing a new drug called zanidatamab to see if it can help people with certain types of cancer that have high levels of HER2 and who have already tried other treatments without success.
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Platform program for evaluating treatments in metastatic HER2-positive breast cancer
This study is testing different new treatments for people with advanced HER2-positive breast cancer to see which ones work best before moving them to larger trials.
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Using HER2 CAR T cells with checkpoint inhibitors for advanced sarcoma
This study is testing a new treatment that combines personalized CAR T cells with immune boosters to see if it helps people with advanced HER2-positive sarcoma.
Related topics
Quick answers
How many HER-2 Protein Overexpression clinical trials are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 4 countries. The most sites are in United States (3 trials), Georgia (1 trial), South Korea (1 trial), Spain (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1: 1, Phase 1/2: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.