Condition

Castration-Resistant Prostate Carcinoma clinical trials and research

• 12Clinical trials
• 1Country

Newest Castration-Resistant Prostate Carcinoma clinical trials

All recruiting trials (12)

• Using 18F-TRX to image solid tumors

  This trial tests whether the 18F-TRX PET tracer can detect tumors in adults with advanced solid tumors such as high‑grade glioma, clear cell renal cell carcinoma, or metastatic castration‑resistant prostate cancer.

  Recruiting Phase 1 University of California, San Francisco · San Francisco, California · NCT06942104

• Targeted treatment for advanced prostate cancer

  This study is testing whether using genetic testing to guide treatment can help people with advanced prostate cancer respond better to new medications.

  Recruiting at 98 sites Phase 2 Alliance for Clinical Trials in Oncology · Birmingham, Alabama and 107 other locations · NCT06632977

• Combining ruxolitinib and enzalutamide for advanced prostate cancer treatment

  This study is testing if combining two medications, ruxolitinib and enzalutamide, can safely help men with advanced prostate cancer that hasn't responded to hormone therapy.

  Recruiting Phase 1/2 University of Michigan Rogel Cancer Center · Chicago, Illinois and 2 other locations · NCT06616155

• Combining Carboplatin with Cabazitaxel for Advanced Prostate Cancer

  This study is testing if adding carboplatin to cabazitaxel chemotherapy can help men with advanced prostate cancer live longer and feel better compared to just using cabazitaxel alone.

  Recruiting at 174 sites Phase 3 SWOG Cancer Research Network · Fayetteville, Arkansas and 173 other locations · NCT06470243

• Re-treatment with a radioactive drug for advanced prostate cancer

  This study is testing if giving a radioactive drug again can help men with advanced prostate cancer who did well on it before feel better and live longer.

  Recruiting Phase 2 Jonsson Comprehensive Cancer Center · Los Angeles, California · NCT06288113

• Using vorinostat and a radioactive treatment for low PSMA metastatic prostate cancer

  This study is testing if adding vorinostat to a radioactive treatment can help people with low PSMA metastatic prostate cancer feel better and improve their outcomes.

  Recruiting Phase 2 Fred Hutchinson Cancer Center · Seattle, Washington · NCT06145633

• Using high levels of testosterone to improve treatment for advanced prostate cancer

  This study is testing if raising testosterone levels can make chemotherapy and a specific drug work better for men with advanced prostate cancer that has stopped responding to other treatments.

  Recruiting Phase 2 University of Washington · Seattle, Washington · NCT06039371

• CAR-T cell therapy with or without radiation for advanced prostate cancer

  This study is testing if a new CAR-T cell therapy, with or without radiation, can help people with advanced prostate cancer live longer and feel better.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT05805371

• Using image-guided biopsies to understand resistance in advanced prostate cancer treatment

  This study is testing how advanced imaging can help doctors understand why some men with hard-to-treat prostate cancer don't respond to a specific therapy, so they can find better treatment options.

  Recruiting Phase 1 Jonsson Comprehensive Cancer Center · Los Angeles, California · NCT05398302

• Using abemaciclib before a radioactive treatment for advanced prostate cancer

  This study is testing if taking abemaciclib before a radioactive treatment can help men with advanced prostate cancer feel better and improve their treatment results.

  Recruiting Phase 1/2 University of California, San Francisco · San Francisco, California · NCT05113537

• Combining cryoablation and radiation therapy for painful bone metastases

  This study is testing if combining a freezing treatment with radiation can help people with painful bone cancer feel better compared to just using radiation alone.

  Recruiting M.D. Anderson Cancer Center · Houston, Texas · NCT04693377

• Investigating DNA Repair and Radium-223 in Advanced Prostate Cancer

  This study is testing if radium-223 can help people with advanced prostate cancer that has spread to the bones, while also looking at how changes in DNA repair might affect the treatment's success.

  Recruiting at 3 sites University of Washington · Baltimore, Maryland and 3 other locations · NCT04489719

Related topics

Quick answers

How many Castration-Resistant Prostate Carcinoma clinical trials are recruiting right now?

12, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in United States. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 4, Phase 1: 3, Phase 1/2: 2, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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