Condition

Stage IV Prostate Cancer AJCC v8 clinical trials and research

• 12Clinical trials
• 5Countries

Newest Stage IV Prostate Cancer AJCC v8 clinical trials

All recruiting trials (12)

• Home versus clinic cancer treatment for Black men with advanced or recurrent prostate cancer

  This Phase II test tries whether giving cancer treatments at home instead of in the clinic is safer and more satisfying for Black men with locally advanced, biochemically recurrent, or metastatic prostate cancer.

  Recruiting Phase 2 Mayo Clinic · Jacksonville, Florida · NCT07073794

• Relugolix to improve PSMA PET/CT imaging in men with high or very high risk prostate cancer

  We are testing whether a short course of relugolix can boost PSMA levels and make PSMA PET/CT scans better at finding cancer in men with high or very high risk prostate cancer.

  Recruiting Phase 2 Mayo Clinic · Scottsdale, Arizona · NCT07025369

• Comparing Abiraterone with Prednisone or Darolutamide for Advanced Prostate Cancer

  This study is testing whether a combination of abiraterone and prednisone works better than darolutamide alone for people with advanced prostate cancer by looking at side effects and changes in PSA levels over a year.

  Recruiting Phase 2 University of California, Davis · Sacramento, California · NCT06173362

• Using bright white light therapy to reduce fatigue and depression in advanced prostate cancer patients

  This study is testing if bright white light therapy can help reduce fatigue and depression in men with advanced prostate cancer who are receiving treatment.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California · NCT05869682

• Peer genetic coaching for African American men with metastatic prostate cancer

  This study tests whether having trained peer coaches can help African American men with metastatic prostate cancer understand and access genetic testing better.

  Recruiting Thomas Jefferson University · Philadelphia, Pennsylvania · NCT05627219

• Peer navigation to support African American men with metastatic prostate cancer during genetic testing

  This trial tests whether a trained peer navigator helps African American men with metastatic prostate cancer better understand and complete genetic testing compared with standard care.

  Recruiting Thomas Jefferson University · Philadelphia, Pennsylvania · NCT05487846

• Using abemaciclib before a radioactive treatment for advanced prostate cancer

  This study is testing if taking abemaciclib before a radioactive treatment can help men with advanced prostate cancer feel better and improve their treatment results.

  Recruiting Phase 1/2 University of California, San Francisco · San Francisco, California · NCT05113537

• Exercise and Fitbit monitoring for prostate cancer patients on hormone therapy

  This study tests if a 16-week exercise program with Fitbit tracking can help prostate cancer patients on hormone therapy improve their heart health and manage other related health risks.

  Recruiting Phase 2 M.D. Anderson Cancer Center · Houston, Texas · NCT05054296

• Effects of vitamin D replacement on immune function in Black prostate cancer patients

  This study is testing if giving vitamin D to Black men with prostate cancer can help their immune system work better and improve their overall health.

  Recruiting at 2 sites Early Phase 1 Mayo Clinic · Scottsdale, Arizona and 1 other locations · NCT05045066

• Combining talazoparib with hormone therapy and abiraterone for prostate cancer treatment

  This study is testing if adding a new drug called talazoparib to standard hormone therapy and abiraterone can help men with advanced prostate cancer do better with their treatment.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California · NCT04734730

• Combining cryoablation and radiation therapy for painful bone metastases

  This study is testing if combining a freezing treatment with radiation can help people with painful bone cancer feel better compared to just using radiation alone.

  Recruiting M.D. Anderson Cancer Center · Houston, Texas · NCT04693377

• Comparing standard therapy with or without surgery or radiation for metastatic prostate cancer

  This study is testing whether adding surgery or radiation to standard treatment helps men with metastatic prostate cancer live longer and feel better compared to just standard treatment alone.

  Recruiting at 297 sites Phase 3 SWOG Cancer Research Network · Gilbert, Arizona and 337 other locations · NCT03678025

Related topics

Quick answers

How many Stage IV Prostate Cancer AJCC v8 clinical trials are recruiting right now?

12, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in United States (12 trials), Chile (1 trial), Colombia (1 trial), Mexico (1 trial), Switzerland (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 6, Early Phase 1: 1, Phase 1/2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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