Condition

Metastatic Prostate Adenocarcinoma clinical trials and research

• 13Clinical trials
• 3Countries

Newest Metastatic Prostate Adenocarcinoma clinical trials

All recruiting trials (13)

• PSMA-targeted therapy with hormone suppression for low-volume metastatic prostate cancer

  This phase II trial tests leuprolide acetate alone versus with 177Lu-PSMA-617 (with or without abiraterone acetate and prednisone) in men with hormone-sensitive, low-volume metastatic prostate cancer.

  Recruiting Phase 2 Mayo Clinic · Rochester, Minnesota · NCT07650240

• Testing Different Dosing Schedules of Lutetium-177Lu PSMA RLT in Advanced Prostate Cancer

  This trial tests if spacing out Lutetium-177Lu PSMA RLT doses adapts to the patient and improves quality of life without shortening life in men with advanced, hormone-resistant prostate cancer.

  Recruiting at 105 sites Phase 3 Alliance for Clinical Trials in Oncology · Anchorage, Alaska and 141 other locations · NCT07200830

• Adding docetaxel to hormonal therapy and apalutamide for metastatic prostate cancer

  This trial tests whether giving the chemotherapy drug docetaxel in addition to hormone therapy and apalutamide helps men with metastatic castration-sensitive prostate cancer live longer.

  Recruiting at 208 sites Phase 3 Alliance for Clinical Trials in Oncology · Tucson, Arizona and 213 other locations · NCT06931340

• Observational study on Lutetium-177 treatment for metastatic prostate cancer

  This study is testing if Lutetium-177 treatment can help men with advanced prostate cancer feel better and understand how their bodies respond to the therapy.

  Recruiting Kuopio University Hospital · Kuopio, Northern Savonia · NCT06850545

• Combining ruxolitinib and enzalutamide for advanced prostate cancer treatment

  This study is testing if combining two medications, ruxolitinib and enzalutamide, can safely help men with advanced prostate cancer that hasn't responded to hormone therapy.

  Recruiting Phase 1/2 University of Michigan Rogel Cancer Center · Chicago, Illinois and 2 other locations · NCT06616155

• Cell therapy combined with enzalutamide for advanced prostate cancer

  This study is testing a new combination of cell therapy and a medication called enzalutamide to see if it helps people with advanced prostate cancer live better and longer.

  Recruiting Phase 1/2 Fred Hutchinson Cancer Center · Seattle, Washington · NCT06236139

• Using vorinostat and a radioactive treatment for low PSMA metastatic prostate cancer

  This study is testing if adding vorinostat to a radioactive treatment can help people with low PSMA metastatic prostate cancer feel better and improve their outcomes.

  Recruiting Phase 2 Fred Hutchinson Cancer Center · Seattle, Washington · NCT06145633

• Using high levels of testosterone to improve treatment for advanced prostate cancer

  This study is testing if raising testosterone levels can make chemotherapy and a specific drug work better for men with advanced prostate cancer that has stopped responding to other treatments.

  Recruiting Phase 2 University of Washington · Seattle, Washington · NCT06039371

• Impact of Exercise and Statins on Cancer Treatment

  This study is testing if doing supervised exercise while taking cancer drugs helps people with metastatic breast, kidney, ovarian, and prostate cancer feel better and respond better to their treatment compared to exercising on their own, and if adding a cholesterol-lowering medication can make it even more effective.

  Recruiting Phase 3 Tampere University Hospital · Tampere, Länsi-Suomi · NCT05796973

• Using abemaciclib before a radioactive treatment for advanced prostate cancer

  This study is testing if taking abemaciclib before a radioactive treatment can help men with advanced prostate cancer feel better and improve their treatment results.

  Recruiting Phase 1/2 University of California, San Francisco · San Francisco, California · NCT05113537

• Exercise and Fitbit monitoring for prostate cancer patients on hormone therapy

  This study tests if a 16-week exercise program with Fitbit tracking can help prostate cancer patients on hormone therapy improve their heart health and manage other related health risks.

  Recruiting Phase 2 M.D. Anderson Cancer Center · Houston, Texas · NCT05054296

• Combining talazoparib with hormone therapy and abiraterone for prostate cancer treatment

  This study is testing if adding a new drug called talazoparib to standard hormone therapy and abiraterone can help men with advanced prostate cancer do better with their treatment.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California · NCT04734730

• Combining Bipolar Androgen Therapy with Radium-223 for advanced prostate cancer

  This study is testing whether combining a new hormone treatment with a radiation therapy can help men with advanced prostate cancer feel better and improve their health.

  Recruiting Phase 2 Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Baltimore, Maryland and 1 other locations · NCT04704505

Related topics

Quick answers

How many Metastatic Prostate Adenocarcinoma clinical trials are recruiting right now?

13, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 3 countries. The most sites are in United States (11 trials), Finland (2 trials), Brazil (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 6, Phase 3: 3, Phase 1/2: 3. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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