Condition

Stage IVA Prostate Cancer AJCC v8 clinical trials and research

• 12Clinical trials
• 8Countries

Newest Stage IVA Prostate Cancer AJCC v8 clinical trials

All recruiting trials (12)

• Comparing heart effects of two hormone therapies in advanced prostate cancer

  This study is testing whether two different hormone treatments for advanced prostate cancer affect heart health differently in men receiving radiation therapy.

  Recruiting at 4 sites Phase 3 Emory University · Atlanta, Georgia and 3 other locations · NCT06650579

• Using advanced imaging to predict lymph node spread in high-risk prostate cancer

  This study is testing a new imaging method to see if it can help doctors predict whether high-risk prostate cancer has spread to lymph nodes before surgery.

  Recruiting Mayo Clinic · Jacksonville, Florida · NCT06389786

• Comparing shorter radiation therapy to standard radiation for high-risk prostate cancer

  This study is testing if a shorter, more intense radiation treatment for high-risk prostate cancer can work just as well as the standard longer treatment.

  Recruiting at 431 sites Phase 3 NRG Oncology · Birmingham, Alabama and 435 other locations · NCT05946213

• High-dose vitamin D for bone health in older prostate cancer patients on hormone therapy

  This study is testing if high-dose vitamin D can help older prostate cancer patients on hormone therapy keep their bones strong and reduce the risk of falls and fractures.

  Recruiting at 51 sites Phase 3 University of Rochester · Newark, Delaware and 50 other locations · NCT05838716

• Using image-guided biopsies to understand resistance in advanced prostate cancer treatment

  This study is testing how advanced imaging can help doctors understand why some men with hard-to-treat prostate cancer don't respond to a specific therapy, so they can find better treatment options.

  Recruiting Phase 1 Jonsson Comprehensive Cancer Center · Los Angeles, California · NCT05398302

• Using abemaciclib before a radioactive treatment for advanced prostate cancer

  This study is testing if taking abemaciclib before a radioactive treatment can help men with advanced prostate cancer feel better and improve their treatment results.

  Recruiting Phase 1/2 University of California, San Francisco · San Francisco, California · NCT05113537

• Exercise and Fitbit monitoring for prostate cancer patients on hormone therapy

  This study tests if a 16-week exercise program with Fitbit tracking can help prostate cancer patients on hormone therapy improve their heart health and manage other related health risks.

  Recruiting Phase 2 M.D. Anderson Cancer Center · Houston, Texas · NCT05054296

• Androgen therapy with or without niraparib for high-risk prostate cancer after radiation

  This study is testing whether adding the drug niraparib to hormone therapy after radiation can help men with high-risk prostate cancer do better than hormone therapy alone.

  Recruiting Phase 2 M.D. Anderson Cancer Center · Houston, Texas · NCT04947254

• Combining high dose-rate brachytherapy and stereotactic body radiotherapy for prostate cancer treatment

  This study is testing whether combining two types of radiation therapy can improve treatment outcomes for men with prostate cancer.

  Recruiting Jonsson Comprehensive Cancer Center · Los Angeles, California · NCT04945642

• Combining talazoparib with hormone therapy and abiraterone for prostate cancer treatment

  This study is testing if adding a new drug called talazoparib to standard hormone therapy and abiraterone can help men with advanced prostate cancer do better with their treatment.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California · NCT04734730

• Combining cryoablation and radiation therapy for painful bone metastases

  This study is testing if combining a freezing treatment with radiation can help people with painful bone cancer feel better compared to just using radiation alone.

  Recruiting M.D. Anderson Cancer Center · Houston, Texas · NCT04693377

• Comparing standard therapy with or without surgery or radiation for metastatic prostate cancer

  This study is testing whether adding surgery or radiation to standard treatment helps men with metastatic prostate cancer live longer and feel better compared to just standard treatment alone.

  Recruiting at 297 sites Phase 3 SWOG Cancer Research Network · Gilbert, Arizona and 337 other locations · NCT03678025

Related topics

Quick answers

How many Stage IVA Prostate Cancer AJCC v8 clinical trials are recruiting right now?

12, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in United States (12 trials), Switzerland (2 trials), Canada (1 trial), Hong Kong (1 trial), Singapore (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 4, Phase 2: 3, Phase 1: 1, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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