Condition

Metastatic Colorectal Carcinoma clinical trials and research

• 15Clinical trials
• 5Countries

Newest Metastatic Colorectal Carcinoma clinical trials

All recruiting trials (15)

• LBL-024 combo therapy for metastatic colorectal cancer in adults

  This trial tests whether adding LBL-024 to a combo of standard cancer drugs can help adults with metastatic colorectal cancer.

  Recruiting Phase 1/2 Nanjing Leads Biolabs Co.,Ltd · Guangzhou, Guangdong and 9 other locations · NCT07791758

• Mitomycin PIPAC plus FOLFIRI vs FOLFIRI/bevacizumab for unresectable peritoneal metastases from appendix or colorectal cancer

  This phase 3 trial tests whether pressurized intraperitoneal aerosolized chemotherapy with mitomycin, given with systemic FOLFIRI, can help patients with unresectable appendix or colorectal cancer that has spread to the abdominal lining, compared with the standard FOLFIRI plus bevacizumab.

  Recruiting Phase 3 City of Hope Medical Center · Goodyear, Arizona and 4 other locations · NCT07271355

• Local treatment for liver metastases in colorectal cancer patients

  This study tests if combining local treatment for liver tumors with regular cancer therapy can help people with colorectal cancer live longer and feel better.

  Recruiting at 6 sites Anhui Provincial Hospital · Chuzhou, Anhui and 5 other locations · NCT06449937

• Predicting how tumors respond to immune therapies using a live diagnostic platform

  This study is testing a new way to predict how well immune therapies will work for patients with different types of solid tumors, including early-stage and metastatic cancers.

  Recruiting at 3 sites Mayo Clinic · Phoenix, Arizona and 2 other locations · NCT06349642

• Comparing home and clinic administration of nivolumab for cancer treatment

  This study tests whether giving cancer patients their treatment at home instead of in a clinic makes them feel better and prefer their care more.

  Recruiting Phase 2 Mayo Clinic · Jacksonville, Florida · NCT06265285

• Testing pump chemotherapy for liver metastases from colorectal cancer

  This study is testing if adding a special type of chemotherapy delivered directly to the liver can help people with colorectal cancer that has spread to the liver live longer and have fewer problems compared to standard chemotherapy alone.

  Recruiting at 54 sites Phase 3 Eastern Cooperative Oncology Group · Birmingham, Alabama and 61 other locations · NCT05863195

• Combining ZEN003694 with Capecitabine for Advanced Cancer Treatment

  This study is testing a new combination of two cancer drugs, ZEN003694 and capecitabine, to see if it can help people with advanced cancers that haven't responded to other treatments.

  Recruiting at 16 sites Phase 1 National Cancer Institute (NCI) · Irvine, California and 21 other locations · NCT05803382

• Evaluating OATD-02 for advanced solid tumors

  This study is testing a new oral medication called OATD-02 to see if it can help people with advanced solid tumors, like colorectal and ovarian cancer, by making their tumors respond better to treatment.

  Recruiting at 3 sites Phase 1 Molecure S.A. · Bydgoszcz, Kuyavian-Pomeranian Voivodeship and 2 other locations · NCT05759923

• CPI-613 combined with hydroxychloroquine and chemotherapy for advanced solid tumors

  This study is testing a new combination of treatments, including CPI-613 and hydroxychloroquine, to see if it can help people with advanced solid tumors that haven't improved with other chemotherapy.

  Recruiting Phase 2 Northwestern University · Chicago, Illinois · NCT05733000

• New imaging technique to evaluate treatment response in colorectal cancer that has spread to the liver

  This study is testing a new imaging method to see if it can help doctors tell how well chemotherapy is working for people with colorectal cancer that has spread to the liver.

  Recruiting M.D. Anderson Cancer Center · Houston, Texas · NCT04796818

• Combining cryoablation and radiation therapy for painful bone metastases

  This study is testing if combining a freezing treatment with radiation can help people with painful bone cancer feel better compared to just using radiation alone.

  Recruiting M.D. Anderson Cancer Center · Houston, Texas · NCT04693377

• Investigation of Encorafenib and Cetuximab for BRAF-mutated Metastatic Colorectal Cancer

  This study is testing if the combination of encorafenib and cetuximab can help people with advanced colorectal cancer that has a specific genetic mutation feel better and live longer after other treatments.

  Recruiting at 70 sites Pierre Fabre Pharma GmbH · Braunau am Inn, Upper Austria and 69 other locations · NCT04673955

• Using pressurized aerosol chemotherapy to treat advanced abdominal cancers

  This study is testing a new way to deliver chemotherapy directly into the abdomen using a special aerosol spray to see if it helps people with advanced abdominal cancers feel better and have fewer side effects.

  Recruiting at 2 sites Phase 1 City of Hope Medical Center · Duarte, California and 2 other locations · NCT04329494

• Using radiation therapy to treat metastatic gastrointestinal cancers

  This study tests if adding radiation therapy to immunotherapy can help people with metastatic gastrointestinal cancers feel better and improve their disease status.

  Recruiting University of California, San Francisco · San Francisco, California and 1 other locations · NCT04221893

• Real-time imaging of tumor blood vessels during surgery

  We will test whether a real-time microscope technique during surgery can show how well blood vessels in adults' solid tumors work and whether that helps predict if systemic cancer medicines can reach the tumor.

  Recruiting Mayo Clinic · Jacksonville, Florida · NCT03823144

Related topics

Quick answers

How many Metastatic Colorectal Carcinoma clinical trials are recruiting right now?

15, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in United States (11 trials), China (2 trials), Poland (1 trial), Austria (1 trial), Germany (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 3, Phase 3: 2, Phase 2: 2, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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