Condition

Biliary Atresia clinical trials and research

• 14Clinical trials
• 9NIH research projects
• 6Countries

Newest Biliary Atresia clinical trials

All recruiting trials (14)

• Umbilical cord stem cells added during Kasai to help biliary atresia

  This early-stage trial tests whether injecting umbilical cord mesenchymal stem cells during Kasai portoenterostomy is safe and helpful for infants with biliary atresia.

  Recruiting Phase 1 Dr Cipto Mangunkusumo General Hospital · Jakarta Pusat, DKI Jakarta · NCT07797673

• See if a computer program can help diagnose cholestasis in newborns using parent-provided stool images

  A computer program is being tested to see if it can correctly identify cholestasis and biliary atresia in newborns by analyzing stool images provided by parents.

  Recruiting Birmingham Women's and Children's NHS Foundation Trust · Birmingham · NCT07697872

• Indocyanine green for diagnosing biliary atresia

  This test tries to see if a harmless fluorescent dye (indocyanine green) can show whether infants under 3 months with cholestasis have blocked bile ducts (biliary atresia).

  Recruiting Phase 1/2 Boston Children's Hospital · Boston, Massachusetts · NCT07513038

• Using near-infrared ICG dye to check bile flow in newborns with cholestasis

  We will give eligible newborns a single IV dose of indocyanine green (ICG) to see if the dye appears in their diapers, which would indicate bile is flowing and the bile ducts are open.

  Recruiting Early Phase 1 University of Alabama at Birmingham · Birmingham, Alabama · NCT07250854

• High-MCT nutritional support for infants with biliary atresia

  We will test whether giving a high medium-chain triglyceride (MCT) formula before and after Kasai surgery helps infants with biliary atresia grow better and recover faster than standard feeding.

  Recruiting Tongji Hospital · Wuhan, Hubei · NCT06764082

• Using oral antibiotics to prevent cholangitis after liver surgery in infants

  This study is testing if giving oral antibiotics to infants after liver surgery can help prevent cholangitis, compared to those who don’t receive the antibiotics.

  Recruiting Children's Hospital of Fudan University · Shanghai, Shanghai Municipality · NCT05925309

• Investigating serum FGF19 levels for predicting outcomes in biliary atresia

  This study is testing if measuring a specific protein in the blood can help doctors predict how well children with biliary atresia will do after surgery.

  Recruiting Children's Hospital of Fudan University · Shanghai, Shanghai Municipality · NCT05848310

• Observing cognitive impairment in children with biliary atresia

  This study looks at children with biliary atresia to see how their liver disease affects their thinking skills and what factors might contribute to any cognitive problems they have.

  Recruiting Copenhagen University Hospital, Rigshospitalet · Copenhagen · NCT05399745

• Nutritional support for infants with biliary atresia

  This study is testing if a special high-fat diet can help infants with biliary atresia grow better and stay healthy after their surgery.

  Recruiting Children's Hospital of Fudan University · Shanghai, Shanghai Municipality · NCT05072626

• Understanding the genetic causes of biliary atresia

  This study is trying to find out the genetic causes of biliary atresia by collecting DNA samples from babies with the condition and their families to see what might lead to this serious liver problem.

  Recruiting University of Pittsburgh · Pittsburgh, Pennsylvania · NCT03273049

• Using vancomycin to treat Primary Sclerosing Cholangitis and Biliary Atresia

  This study is testing if the antibiotic vancomycin can help improve the health of people with Biliary Atresia and Primary Sclerosing Cholangitis while also looking at how it affects the gut bacteria.

  Recruiting Phase 1 Sacramento Pediatric Gastroenterology · Sacramento, California · NCT02137668

• Registry for patients with rare diseases

  This study is creating a central registry for people with rare diseases to help connect them with researchers and improve treatments.

  Recruiting Sanford Health · Sioux Falls, South Dakota · NCT01793168

• Understanding Biliary Atresia in Children

  This study is trying to learn more about biliary atresia in children by collecting health information and samples to see what causes the disease and how it affects their lives.

  Recruiting at 9 sites Arbor Research Collaborative for Health · Los Angeles, California and 15 other locations · NCT00345553

• Database of infants with cholestasis

  This study is creating a database of health information and samples from infants with liver diseases to help researchers learn more about these conditions and improve treatments.

  Recruiting at 9 sites Arbor Research Collaborative for Health · Los Angeles, California and 15 other locations · NCT00061828

NIH-funded research (9)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Genetic factors in virus-related biliary atresia in children

  A study to understand how viral infections may trigger biliary atresia in very young children and how genetics influence this process.

  NIH research Stanford University · Stanford, United States · NIH-11471608

• MMP7-Positive Liver Cells Driving Fibrosis in Biliary Atresia

  This study explores a specific liver cell type marked by MMP7 to understand why scarring progresses in biliary atresia and how it might be slowed.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11438027

• How genes may cause biliary atresia

  This project looks at how changes in a gene called PKD1L1 might lead to biliary atresia in babies and to later bile-duct inflammation.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11372330

• Bifidobacterium breve to support bile flow in infants with cholestasis and biliary atresia

  A tiny study in babies with biliary atresia or related cholestasis tests a safe probiotic supplement (B. breve) to help bile flow after a surgical procedure.

  NIH research Baylor College of Medicine · Houston, United States · NIH-11356887

• Mechanisms of neutrophil NETs and their role in biliary fibrosis in biliary atresia

  A study to understand how certain white blood cells and their networks contribute to scarring in the bile ducts of infants with biliary atresia.

  NIH research Medical College of Wisconsin · Milwaukee, United States · NIH-11329986

• Understanding how immune cells contribute to liver scarring in infants with biliary atresia

  This research explores how certain immune cells called neutrophils cause liver scarring in babies born with biliary atresia.

  NIH research Medical College of Wisconsin · Milwaukee, United States · NIH-11141644

• Investigating the role of the microbiome in biliary atresia

  This study is looking at how the bacteria in the gut might affect the health of babies with biliary atresia, a liver condition, by collecting stool samples to see if there are differences between those who do and don’t have successful bile flow after surgery, with the hope of finding ways to improve their care.

  NIH research Baylor College of Medicine · Houston, United States · NIH-11074603

• Understanding how immune cells contribute to liver damage in infants with biliary atresia

  This study is looking at how certain immune cells called neutrophils might be causing liver damage in babies with biliary atresia, a condition that affects their bile ducts, and it hopes to find new ways to help treat this condition.

  NIH research Medical College of Wisconsin · Milwaukee, United States · NIH-10938525

• Understanding the causes and outcomes of biliary atresia in infants

  This study is looking into biliary atresia, a liver condition in babies, to understand how it affects their health and treatment, with the goal of finding better ways to help kids with this condition live healthier lives.

  NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-10824147

Related topics

Quick answers

How many Biliary Atresia clinical trials are recruiting right now?

14, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in United States (7 trials), China (4 trials), Canada (2 trials), Denmark (1 trial), United Kingdom (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 2, Phase 1/2: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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