Nutritional support for infants with biliary atresia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on infants diagnosed with biliary atresia, a condition that can lead to liver failure. It aims to assess the impact of high medium-chain triglyceride nutritional support on the growth and nutritional status of these infants, particularly during the critical period following the Kasai procedure. The study will monitor the nutritional outcomes and growth rates of infants receiving specialized nutritional therapy, addressing the common complications of malnutrition associated with biliary atresia. The research is conducted at a single center, the Children's Hospital of Fudan University, and aims to establish better nutritional practices for this vulnerable population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

The Kasai procedure for infants with biliary atresia under the age of 3 months.

Exclusion Criteria:

* Complicated with cirrhosis, hepatitis, or other hepatic disorders;
* Complicated with other systemic serious diseases (such as congenital multiple malformations, chromosome abnormalities)

Where it's running

• Children's Hospital of Fudan University
  Shanghai, Shanghai Municipality, China Recruiting

Study contacts

• Study coordinator: Tian Qian, M.D. PhD
• Email: drqiantian@fudan.edu.cn
• Phone: +8602164931981

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Umbilical cord stem cells added during Kasai to help biliary atresia

  This early-stage trial tests whether injecting umbilical cord mesenchymal stem cells during Kasai portoenterostomy is safe and helpful for infants with biliary atresia.

  Recruiting Phase 1 Dr Cipto Mangunkusumo General Hospital · Jakarta Pusat, DKI Jakarta · NCT07797673

• See if a computer program can help diagnose cholestasis in newborns using parent-provided stool images

  A computer program is being tested to see if it can correctly identify cholestasis and biliary atresia in newborns by analyzing stool images provided by parents.

  Recruiting Birmingham Women's and Children's NHS Foundation Trust · Birmingham · NCT07697872

• Automated oxygen control for preterm babies on non-invasive support

  This trial tests whether closed-loop automated oxygen control helps preterm babies on non-invasive ventilation reach target oxygen levels more often and spend less time on supplemental oxygen compared with manual control.

  Recruiting King's College Hospital NHS Trust · London · NCT07622563

• Indocyanine green for diagnosing biliary atresia

  This test tries to see if a harmless fluorescent dye (indocyanine green) can show whether infants under 3 months with cholestasis have blocked bile ducts (biliary atresia).

  Recruiting Phase 1/2 Boston Children's Hospital · Boston, Massachusetts · NCT07513038

• Using near-infrared ICG dye to check bile flow in newborns with cholestasis

  We will give eligible newborns a single IV dose of indocyanine green (ICG) to see if the dye appears in their diapers, which would indicate bile is flowing and the bile ducts are open.

  Recruiting Early Phase 1 University of Alabama at Birmingham · Birmingham, Alabama · NCT07250854

• Investigating veinous lactate levels to predict complications after surgery in infants

  This study is testing if measuring lactate levels in the blood after surgery can help predict complications in infants aged 0-1 year.

  Recruiting Hôpital Armand Trousseau · Paris · NCT06909227

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.