Effect of PENG Block on Pain After Hip Surgery

A Blinded Randomized Study Investigating the Effect of Pericapsular Nerve Group (PENG) Block on Postoperative Pain After Peri-acetabular Osteotomy

Phase 4 Interventional Rigshospitalet, Denmark · NCT06406010

This study is testing if a new pain relief method called the PENG block can help people feel less pain after hip surgery compared to a placebo.

Quick facts

PhasePhase 4
Study typeInterventional
Enrollment90 (estimated)
Ages18 Years and up
SexAll
SponsorRigshospitalet, Denmark Academic / other
Locations1 site (Copenhagen)
Trial IDNCT06406010 on ClinicalTrials.gov

What this trial studies

This study investigates the impact of the pericapsular nerve group (PENG) block on postoperative pain management in patients undergoing peri-acetabular osteotomy (PAO). Participants will receive either ropivacaine or saline as a placebo to assess the effectiveness of the PENG block in reducing pain after surgery. The study aims to provide insights into the analgesic benefits of this novel regional anesthesia technique, which targets specific nerves innervating the hip joint. By comparing outcomes between the two groups, the research seeks to enhance postoperative pain management strategies for hip dysplasia surgeries.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older scheduled for peri-acetabular osteotomy under general anesthesia.

Not a fit: Patients with known allergies to ropivacaine or those using certain medications like opioids or gabapentin may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could significantly reduce postoperative pain for patients undergoing hip surgery, improving recovery and quality of life.

How similar studies have performed: Other studies have shown promising results with similar nerve block techniques, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients ≥ 18 years old
2. Informed consent
3. Scheduled for periacetabular osteotomy under general anesthesia with intubation
4. American Society of Anesthesiologists (ASA) physical status classification I to III
5. Can read and understand Danish

Exclusion Criteria:

1. Known allergy to ropivacaine
2. Daily use of opioids, gabapentin or tricyclic antidepressant (regardless of dose) within the last four weeks prior to surgery
3. Contraindications to Celocoxib, NSAIDs or paracetamol

Where this trial is running

Copenhagen

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Anesthesia, Local
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.