Clinical trial Recruiting at 1 site Phase 4 Interventional Ages 18 and up

Effect of PENG Block on Pain After Hip Surgery

Official title: A Blinded Randomized Study Investigating the Effect of Pericapsular Nerve Group (PENG) Block on Postoperative Pain After Peri-acetabular Osteotomy

Run by Copenhagen University Hospital, Rigshospitalet · NCT06406010 · Data updated 2026-11-12

This study is testing if a new pain relief method called the PENG block can help people feel less pain after hip surgery compared to a placebo.

Quick facts

PhasePhase 4
Study typeInterventional
Ages18 Years and up
SexAll
Enrollment90 (estimated)
SponsorCopenhagen University Hospital, Rigshospitalet
Academic / other
Locations1 site (Copenhagen)
StatusRecruiting
StartedAugust 19, 2024
Main results expectedFebruary 1, 2027
Study endsMarch 1, 2027
Registry record updatedSeptember 15, 2026
Trial IDNCT06406010 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older scheduled for peri-acetabular osteotomy under general anesthesia.

Probably not a fit

Patients with known allergies to ropivacaine or those using certain medications like opioids or gabapentin may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the impact of the pericapsular nerve group (PENG) block on postoperative pain management in patients undergoing peri-acetabular osteotomy (PAO). Participants will receive either ropivacaine or saline as a placebo to assess the effectiveness of the PENG block in reducing pain after surgery. The study aims to provide insights into the analgesic benefits of this novel regional anesthesia technique, which targets specific nerves innervating the hip joint. By comparing outcomes between the two groups, the research seeks to enhance postoperative pain management strategies for hip dysplasia surgeries.

Why it matters

Potential benefit: If successful, this study could significantly reduce postoperative pain for patients undergoing hip surgery, improving recovery and quality of life.

How similar studies have gone: Other studies have shown promising results with similar nerve block techniques, suggesting potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients ≥ 18 years old
2. Informed consent
3. Scheduled for periacetabular osteotomy under general anesthesia with intubation
4. American Society of Anesthesiologists (ASA) physical status classification I to III
5. Can read and understand Danish

Exclusion Criteria:

1. Known allergy to ropivacaine
2. Daily use of opioids, gabapentin or tricyclic antidepressant (regardless of dose) within the last four weeks prior to surgery
3. Contraindications to Celocoxib, NSAIDs or paracetamol

Where it's running

  • Rigshospitalet
    Copenhagen, Denmark
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.