Condition

Acute Lymphoblastic Leukemia (ALL) clinical trials and research

• 17Clinical trials
• 3NIH research projects
• 27Countries

Newest Acute Lymphoblastic Leukemia (ALL) clinical trials

All recruiting trials (17)

• CAYA cancer patients in LMICs: a forward-looking observation of care and outcomes

  This study follows children, teens, and young adults with cancer in low- and middle-income countries to see how routine care affects treatment, access, and outcomes over time.

  Recruiting Resonance, Inc. · Yerevan and 5 other locations · NCT07632014

• First-in-human testing of 4A10 for relapsed or hard-to-treat ALL and lymphoblastic lymphoma

  This early-stage trial tests a new antibody therapy called 4A10 in patients with relapsed or hard-to-treat acute lymphoblastic leukemia or lymphoblastic lymphoma to see if it is safe and how the body handles it.

  Recruiting at 5 sites Phase 1 Allterum Therapeutics, Inc · Aurora, Colorado and 6 other locations · NCT07586618

• Plasma cell-free DNA in children with ALL to help monitor disease

  This study tests whether measuring tumor DNA in blood can help monitor acute lymphoblastic leukemia in kids without needing frequent bone-marrow tests.

  Recruiting at 2 sites Assistance Publique - Hôpitaux de Paris · Paris and 1 other locations · NCT07483476

• Laughter and fun yoga to ease chemotherapy pain in children

  This tests whether a home-based program of laughter and kid-friendly yoga can lower pain in children aged 2–10 who are receiving chemotherapy for acute lymphoblastic leukemia.

  Recruiting Beirut Arab University · Sidon · NCT07327138

• Tracking and predicting chemotherapy-related nerve damage in children with acute lymphoblastic leukemia

  Researchers will track how vincristine-related nerve damage develops over time in children (ages 8–17) with acute lymphoblastic leukemia and try to identify factors that predict different symptom patterns.

  Recruiting at 3 sites The Hong Kong Polytechnic University · Zhengzhou, Henan and 2 other locations · NCT07326930

• Optimizing and Unifying Management of HSCT in Pediatric ALL

  This trial tests a harmonized HSCT approach for children and young people with ALL, aiming to reduce transplant-related risks and improve long-term outcomes.

  Recruiting at 2 sites Phase 2/3 Bambino Gesù Hospital and Research Institute · Vienna and 8 other locations · NCT07297914

• Child and Young Adult (CAYA) Cancer Outcomes Review

  This project looks at past treatment results to see what affects outcomes for children and young adults (ages 0–21) with leukemia and other cancers treated at participating centers in low- and middle-income countries.

  Recruiting at 5 sites Resonance, Inc. · Yerevan and 6 other locations · NCT07246213

• ALL Backbone in AYAs

  Aims to see if a chemotherapy regimen can safely and effectively treat newly diagnosed Philadelphia chromosome-negative ALL in adolescents and young adults.

  Recruiting Phase 2 Dana-Farber Cancer Institute · Boston, Massachusetts · NCT07227584

• Noninvasive ear vagus nerve stimulation for insomnia in adult survivors of childhood ALL

  This tests whether nightly noninvasive ear vagus nerve stimulation can improve sleep in adult survivors of childhood acute lymphoblastic leukemia who have moderate to severe insomnia.

  Recruiting St. Jude Children's Research Hospital · Memphis, Tennessee · NCT07191119

• Newly diagnosed low‑risk pediatric B‑cell ALL treatment with short blinatumomab courses

  This protocol will try giving two short 14‑day courses of blinatumomab early and during consolidation for children with newly diagnosed low‑risk B‑cell ALL to allow less intensive later chemotherapy when deep MRD negativity is achieved.

  Recruiting Phase 2/3 Institute of Hematology & Blood Diseases Hospital, China · Hefei, Anhui and 26 other locations · NCT06882057

• High-dose irradiation followed by immunotherapy for high-risk leukemia patients

  This study is testing a new treatment that combines high-dose radiation with special immune cells to see if it helps patients with high-risk leukemia do better after a stem cell transplant.

  Recruiting University Of Perugia · Perugia, PG · NCT06845592

• New treatment options for children with high-risk B-cell leukemia

  This study is testing two different treatment options for children with high-risk B-cell leukemia to see which one helps them get better and live longer.

  Recruiting Phase 2/3 Institute of Hematology & Blood Diseases Hospital, China · Hefei, Anhui and 26 other locations · NCT06764238

• Combining stem cell transplantation with CD19-CART for treating high-risk leukemia in adults

  This study is testing a new treatment that combines stem cell transplant with a special type of immune therapy to see if it helps adults with high-risk leukemia feel better and stay in remission.

  Recruiting Phase 2 Institute of Hematology & Blood Diseases Hospital, China · Tianjin, Tianjin Municipality · NCT06608342

• Evaluation of CAR-T cell therapy in certain blood cancers

  This study is testing how well CAR-T cell therapy works and lasts in patients with certain types of blood cancers, while also looking for signs that could predict how they respond to treatment and any side effects they might have.

  Recruiting Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · Brescia · NCT05366569

• Feasibility of a new approach to control nausea in children with leukemia

  This study is testing a new program to help parents learn how to better manage nausea in children with leukemia who are undergoing chemotherapy.

  Recruiting at 4 sites The Hospital for Sick Children · Los Angeles, California and 3 other locations · NCT04929899

• Improving treatment for high-risk childhood relapsed leukemia

  This study is testing a new treatment plan that combines a drug called bortezomib with standard therapies to see if it can help children and teens with high-risk relapsed leukemia do better and live longer.

  Recruiting at 10 sites Phase 2 Charite University, Berlin, Germany · Clayton, Victoria and 14 other locations · NCT03590171

• Access and distribution of unlicensed cryopreserved cord blood units

  This study is testing how well unlicensed frozen cord blood units work for helping both kids and adults with blood cancers recover after a transplant.

  Recruiting at 113 sites Center for International Blood and Marrow Transplant Research · Birmingham, Alabama and 141 other locations · NCT01351545

NIH-funded research (3)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Disparities in childhood ALL: how patients' reports, biology, and neighborhoods shape outcomes

  This project explores why Latino children with acute lymphoblastic leukemia have worse outcomes by looking at patient-reported experiences, epigenetic patterns, and neighborhood factors.

  NIH research Baylor College of Medicine · Houston, United States · NIH-11420849

• New Approaches for High-Risk Acute Lymphoblastic Leukemia

  This project looks for new ways to treat aggressive forms of acute lymphoblastic leukemia (ALL) in adults, especially those that are hard to treat with current medicines.

  NIH research Thomas Jefferson University · Philadelphia, United States · NIH-11125897

• Targeting a specific protein to improve treatment for certain types of leukemia

  This study is looking at new ways to treat a tough type of leukemia called Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL) by focusing on a protein called CDK6, which helps cancer cells grow, to see if targeting it can make treatments work better and help prevent the cancer from coming back, and patients m

  NIH research Thomas Jefferson University · Philadelphia, United States · NIH-10867341

Related topics

Quick answers

How many Acute Lymphoblastic Leukemia (ALL) clinical trials are recruiting right now?

17, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 27 countries. The most sites are in United States (5 trials), China (4 trials), Italy (4 trials), France (3 trials), Hong Kong (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2/3: 3, Phase 2: 3, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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