Condition

B-cell Acute Lymphoblastic Leukemia (B-ALL) clinical trials and research

• 10Clinical trials
• 14Countries

Newest B-cell Acute Lymphoblastic Leukemia (B-ALL) clinical trials

All recruiting trials (10)

• Vaccine protection after blinatumomab in children with B-ALL

  This project will see if children and young adults (ages 1–21) with B-cell acute lymphoblastic leukemia who received blinatumomab keep protective immunity from routine childhood vaccines and whether revaccination restores immunity when levels are low.

  Recruiting at 2 sites Arkansas Children's Hospital Research Institute · Little Rock, Arkansas and 1 other locations · NCT07422337

• GT801 injection for adults with relapsed/refractory CD19-positive B-cell cancers and autoimmune hemolytic anemia

  This trial will test whether GT801 injections help adults with CD19-positive B-cell cancers (B-ALL, CLL, B-NHL) or autoimmune hemolytic anemia that have returned or not responded to prior treatments.

  Recruiting Early Phase 1 Grit Biotechnology · Zhengzhou, Henan and 1 other locations · NCT07205315

• AZD4512 alone or with other cancer drugs for relapsed/refractory CD22-positive B‑cell ALL

  This trial will test whether AZD4512, given alone, is safe and can help adults and adolescents with relapsed or refractory CD22-positive B‑cell acute lymphoblastic leukemia.

  Recruiting at 21 sites Phase 1/2 AstraZeneca · Duarte, California and 26 other locations · NCT07109219

• Long-term health and quality of life after CD19 CAR T-cell therapy in B-ALL survivors

  This project will test whether standardized health checks can be done for children, adolescents, and young adults who are at least two years past CD19 CAR T-cell treatment for B-ALL.

  Recruiting St. Jude Children's Research Hospital · Memphis, Tennessee · NCT07048535

• Newly diagnosed low‑risk pediatric B‑cell ALL treatment with short blinatumomab courses

  This protocol will try giving two short 14‑day courses of blinatumomab early and during consolidation for children with newly diagnosed low‑risk B‑cell ALL to allow less intensive later chemotherapy when deep MRD negativity is achieved.

  Recruiting Phase 2/3 Institute of Hematology & Blood Diseases Hospital, China · Hefei, Anhui and 26 other locations · NCT06882057

• Nutrition and exercise during hospital induction for adults with Philadelphia chromosome–negative B‑ALL

  This program will test whether guided nutrition and in-hospital exercise during induction therapy help adults with Philadelphia chromosome–negative B‑ALL keep muscle and limit excess body fat.

  Recruiting University of Chicago · Chicago, Illinois · NCT06785324

• New treatment options for children with high-risk B-cell leukemia

  This study is testing two different treatment options for children with high-risk B-cell leukemia to see which one helps them get better and live longer.

  Recruiting Phase 2/3 Institute of Hematology & Blood Diseases Hospital, China · Hefei, Anhui and 26 other locations · NCT06764238

• JY231 injection for treating B-cell acute lymphoblastic leukemia

  This study is testing a new injection called JY231 to see if it can safely help people with B-cell acute lymphoblastic leukemia feel better.

  Recruiting Early Phase 1 920th Hospital of Joint Logistics Support Force of People's Liberation Army of China · Kunming, Yunnan · NCT06514768

• Treatment of B-cell Acute Lymphoblastic Leukemia with AZD0486

  This study is testing a new drug called AZD0486 to see if it can help people with relapsed or hard-to-treat B-cell Acute Lymphoblastic Leukemia after they have already tried other treatments.

  Recruiting at 59 sites Phase 1/2 AstraZeneca · Birmingham, Alabama and 82 other locations · NCT06137118

• Using a new method to create CAR T cells for treating pediatric B-ALL

  This study is testing a new way to make CAR T cells faster and safer for kids with B cell Acute Lymphoblastic Leukemia (B-ALL) to see if it helps them get better treatment more quickly.

  Recruiting Phase 1/2 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT05480449

Related topics

Quick answers

How many B-cell Acute Lymphoblastic Leukemia (B-ALL) clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 14 countries. The most sites are in China (6 trials), United States (6 trials), Hong Kong (2 trials), Australia (2 trials), Canada (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 3, Phase 2/3: 2, Early Phase 1: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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