Automated lung recruitment during major laparoscopic colorectal cancer surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, randomized, single-center trial comparing automated intraoperative lung recruitment maneuvers delivered by modern anesthesia ventilators with standard mechanical ventilation in adults undergoing elective major laparoscopic colorectal cancer surgery. Patients aged 18–80 with ASA physical status I–III will be randomized 1:1 after arrival in the operating room to receive either programmed automated recruitment maneuvers or standard ventilation without recruitment. Lung ultrasonography will be used at predefined perioperative time points to quantify atelectasis using a lung ultrasound score, and postoperative pulmonary complications and hemodynamic events will be recorded. Key exclusions include severe COPD, BMI>40 kg/m², advanced heart failure, prior thoracic surgery, preoperative oxygen requirement, conversion to open surgery, or significant hemodynamic instability during maneuvers.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age between 18 and 80 years
* Scheduled for elective laparoscopic colorectal cancer surgery
* American Society of Anesthesiologists (ASA) physical status I-III

Exclusion Criteria:

* ASA physical status IV or higher
* Pregnancy
* Body mass index (BMI) \> 40 kg/m²
* Severe chronic obstructive pulmonary disease (COPD), GOLD stage III-IV
* Advanced heart failure with left ventricular ejection fraction \<35%
* Previous thoracic surgery
* Preoperative requirement for supplemental oxygen therapy
* Refusal or inability to provide informed consent
* Intraoperative conversion to open surgery
* Development of significant hemodynamic instability during lung recruitment maneuvers

Where it's running

• SBÜ Bakırköy Dr. Sadi Konuk Eğitim ve Araştırma Hastanesi
  Istanbul, Bakırkoy, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Sena Gökçe Karataş
• Email: senagokce_96@outlook.com
• Phone: +90 212 414 71 71

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.