Feasibility of a perinatal smoking and cannabis cessation program
Official title: Partnering With Pregnant and Postpartum People to Co-Create a Novel Intervention to Reduce Tobacco and Cannabis Use
Run by University of Pittsburgh · NCT07489443 · Data updated 2026-11-12
This study tests a perinatal program to help pregnant people quit tobacco and cannabis and stay smoke-free after birth.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 25 (estimated) |
| Sponsor | University of Pittsburgh Academic / other |
| Locations | 1 site (Pittsburgh, Pennsylvania) |
| Status | Recruiting |
| Started | June 17, 2026 |
| Main results expected | April 2027 |
| Study ends | October 2027 |
| Registry record updated | July 6, 2026 |
| Trial ID | NCT07489443 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are English-speaking pregnant individuals up to 26 weeks gestation who regularly use tobacco and cannabis and intend to continue their pregnancy.
✕Probably not a fit
Individuals not using tobacco or cannabis, those beyond 26 weeks gestation, or those unable to participate in English may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional feasibility trial aims to address tobacco and cannabis use during pregnancy and postpartum. Participants are pregnant individuals up to 26 weeks gestation who use combustible tobacco weekly and have used cannabis, and who plan to remain pregnant and communicate in English. The study provides perinatal smoking cessation treatment plus maintenance sessions, with a focus on addressing prenatal depressive symptoms to support cessation efforts. Conducted at Bellefield Towers in Pittsburgh with University of Pittsburgh as the lead sponsor and NIDA collaboration, the trial will assess acceptability and practicality of the approach rather than efficacy outcomes. Results will inform future larger trials on integrated cessation support in this population.
Why it matters
Potential benefit: If successful, the program could help pregnant people reduce or stop tobacco and cannabis use and improve postpartum smoke-free status.
How similar studies have gone: Previous work suggests behavioral cessation support can be feasible in perinatal populations, but this specific integrated tobacco and cannabis approach in pregnancy is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Confirmed pregnant * Under 26 weeks gestation * Plan to remain pregnant * English speaking * Use of combustible tobacco at least once a week during pregnancy, or at least once a week in the 3 months before pregnancy if stopped * Use of cannabis at any frequency during pregnancy or in the 3 months before pregnancy if stopped Exclusion Criteria: * Current opioid use or active treatment for Opioid Use Disorder * Unable to provide informed consent in English * Under 18 years old
Where it's running
-
Bellefield Towers
Pittsburgh, Pennsylvania, United States Recruiting
Study contacts
- Principal investigator: Natacha De Genna — University of Pittsburgh
- Study coordinator: Project Coordinator
- Email: parentas@upmc.edu
- Phone: 412-301-3848
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.