Quitting Matters: a smoking quit program for people living with HIV

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Participants who smoke and are receiving HIV care will be randomized to use one of two smartphone smoking-cessation apps for about 24 weeks while receiving nicotine replacement therapy (patches and gum). The trial includes five video-call visits during which staff collect questionnaires, interviews, and breath or saliva samples to measure smoking outcomes. One app is specifically tailored for people with HIV and the other is a general quit app, allowing comparison of effectiveness and implementation barriers. The study also documents feasibility and factors that affect adoption of digital therapeutics in this population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Self-reported daily cigarette smoking over the past 30 days
2. Self-reported HIV status
3. Age 18 or older
4. Desire to quit smoking
5. Willing and medically eligible to use NRT
6. Currently receiving HIV care
7. Currently owning an Android or iOS smartphone

Exclusion Criteria:

1. Current acute psychotic episode or unsafe to participate in the study
2. Pregnant or intending to become pregnant in the next 6 months
3. Currently receiving any pharmacological and/or behavioral intervention or counseling for smoking cessation
4. Any medical condition or medication that could compromise subject safety, as determined by the PIs and/or study physician
5. Not able to fluently speak and write in English
6. Hearing, comprehension, visual, speech, or motor limitations that preclude study participation

Where it's running

• Wake Forest University, Implementation Science
  Winston-Salem, North Carolina, United States Recruiting

Study contacts

• Principal investigator: Roger Vilardaga Viera, Ph.D. — Wake Forest University Health Sciences
• Study coordinator: Roger Vilardaga Vierra, Ph.D.
• Email: Roger.Vilardaga@wfusm.edu
• Phone: 336-716-1495

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Communal coping in couples where both partners smoke during a quit attempt

  This project tests whether couples who tackle quitting as a team (communal coping) fare better when one partner in a smoking couple tries to quit.

  Recruiting University of Colorado, Denver · Denver, Colorado · NCT07553962

• Extended tobacco support for people experiencing homelessness

  This program tests whether extending tobacco treatment to 6 months with pharmacist counseling, monthly nicotine replacement deliveries, and phone wellness coaching helps adults experiencing homelessness quit smoking compared with a 3-month package.

  Recruiting Phase 4 University of California, San Francisco · San Francisco, California · NCT07148232

• A program to help people quit smoking using CBT and mindfulness audio support

  This study is testing if combining text messages for quitting smoking with mindfulness audio support helps people stop smoking better than just using text messages alone.

  Recruiting Sir Run Run Shaw Hospital · Hangzhou · NCT06901713

• AI Molar Mind to help people quit smoking with oral health feedback

  This study will test whether AI Molar Mind, a digital tool that reviews your oral health and gives personalized feedback, can help adults who smoke at least five cigarettes a day quit smoking.

  Recruiting Fayoum University · Fayoum, Alexandria Governorate · NCT06762210

• Smoking cessation for parents with health navigator support to tackle social needs

  We’re testing a program that helps parents quit smoking and also addresses their social challenges to reduce kids’ exposure to secondhand smoke.

  Recruiting at 3 sites St. Justine's Hospital · Montreal, Quebec and 2 other locations · NCT06651684

• Optimizing a smoking cessation program for people living with HIV

  This study is trying to find the best way to help people living with HIV quit smoking by using a mix of support methods like counseling, mentoring, and text reminders.

  Recruiting Phase 4 New York University · New York, New York · NCT06598397

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.