Telegram-based smoking-cessation support after heart attack

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicenter randomized, assessor-blinded study compares a 6-month Telegram-based behavioral support program with standard care for adults who smoked and recently had an acute myocardial infarction. Participants are randomized to receive either personalized motivational messages, cognitive-behavioral techniques for cravings, and relapse prevention via Telegram, or standard care plus basic surveys. The primary outcome is 30-day abstinence at 6 months, verified by blinded telephone contact and a relative's report; secondary outcomes include changes in smoking behavior, nicotine dependence, motivation, and engagement with the intervention. Approximately 142 participants are enrolled from inpatient cardiology departments to assess whether the digital intervention improves long-term cessation in post-MI patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Willing and able to provide written informed consent.
* Age 18 years or older.
* Hospitalization with a confirmed diagnosis of acute myocardial infarction (MI), including both ST-elevation MI (STEMI) and non-ST-elevation MI (NSTEMI), enrolment occurring either during index hospitalization or within 1 month post-MI at an outpatient visit
* Current smoker at the time of index MI: self-reported smoking of at least one cigarette per day in the month prior to hospitalization.
* Regular user of the Telegram messenger application (app installed on a personal smartphone).
* Possession of a smartphone with internet access and a valid phone number.
* Ability and willingness to provide contact information for a close relative or cohabiting person who can verify smoking status at follow-up.

Exclusion Criteria:

* Smoking cessation more than 1 month prior to the index MI hospitalization.
* Physical or cognitive impairment that prevents the use of a smartphone (e.g., severe visual/hearing impairment, inability to read or respond to messages).
* Inability to read and understand the Russian language fluently.
* Comorbid condition with a life expectancy of less than 1 year.
* Active severe mental illness (e.g., psychosis, severe untreated depression) that would impede understanding of the protocol or adherence.
* Unwillingness or inability to provide contact details for a close relative for outcome verification.

Where it's running

• Ulyanovsk Regional Clinical Hospital
  Ulyanovsk, Russia Recruiting
• Ulyanovsk Regional Clinical Hospital
  Ulyanovsk, Ulyanovsk Oblast, Russia Not yet recruiting

Study contacts

• Principal investigator: Mikhail Kuznetsov, MD — Ulyanovsk Regional Clinical Hospital
• Study coordinator: Mikhail A. Kuznetsov, MD
• Email: mihkuzn@gmail.com
• Phone: +79170610352

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.