Evaluating vascular aging after COVID-19 infection

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to assess the effects of COVID-19 on arterial stiffness and vascular aging by conducting non-invasive evaluations of vascular and cardiac function in patients six and twelve months post-infection. Eligible participants will include adults diagnosed with COVID-19, with varying degrees of hospitalization, and will undergo assessments to measure carotid-femoral pulse-wave velocity. Additionally, cardiovascular events and mortality data will be collected over a period of 10 years to understand long-term impacts.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* age \>18 years, both sexes;
* written informed consent;
* affiliation to a social security regime;
* a recent diagnosis of COVID19 (6±3 months) proven by PCR or serology (for group 1,2,3)
* hospitalization in intensive care unit for COVID19 (for group 1)
* hospitalization in a medicine unit for COVID19 (for group 2)
* no hospitalization for COVID19 or hospitalization less than 24h (for group 3)
* a negative test for SARS-nCOV2 infection (PCR or serology)(for group 4)

Exclusion Criteria:

* Age \<18 years
* Inability to express consent of the study
* Diseases carrying out a life -expectancy \<1 year according to clinical judgment
* Pregnancy and breastfeeding
* Foreseen inability to attend scheduled visits

Where it's running

• CHRU Nancy
  Nancy, France Recruiting
• Hôpital Européen Georges Pompidou - APHP
  Paris, France Recruiting
• CHU Rouen
  Rouen, France Recruiting

Study contacts

• Principal investigator: Pierre BOUTOUYRIE, MD PHD — Assistance Publique - Hôpitaux de Paris
• Study coordinator: Rosa Maria BRUNO, MD
• Email: rosa-maria.bruno@inserm.fr
• Phone: +33 1 53 98 79 67

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.