Biobank of stem cells and biomarkers for cardiovascular disease
Blood Biomarkers From Ethnically Diverse Cardiovascular Patients
This study is creating a bank of stem cells and blood samples from people with heart disease to help researchers learn more about the condition and find better treatments.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's Academic / other |
| Locations | 1 site (London, Ontario) |
| Trial ID | NCT06371937 on ClinicalTrials.gov |
What this trial studies
This project aims to create a clinical database and biobank of induced pluripotent stem cells (iPSCs) derived from the blood of participants with cardiovascular diseases. It will recruit individuals from diverse racial and ethnic backgrounds, ensuring equal representation of both sexes. The study will analyze blood samples for protein biomarkers and genetic factors associated with cardiovascular disease, facilitating a deeper understanding of the disease mechanisms. The resulting iPSC biobank and clinical data will serve as valuable resources for future cardiovascular research.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 to 80 with various forms of cardiovascular disease.
Not a fit: Patients under 18 years of age or those unable to provide consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this initiative could lead to improved understanding and treatment options for cardiovascular diseases.
How similar studies have performed: Other studies utilizing iPSCs for cardiovascular research have shown promise, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult (18 to 80 years of age) * Cardiovascular Disease (CVD) * Cerebrovascular Disease (CBD) * Peripheral Vascular Disease (PVD) * Inherited Arrhythmias * Cardiomyopathies * Congenital Heart Disease (CHD) * Aortopathy * Hypertension * Cardiometabolic Disease (CMD) Exclusion Criteria: * Younger than 18 years of age. * Patients not able to provide consent.
Where this trial is running
London, Ontario
- London Regional Health Science Centre — London, Ontario, Canada (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.