SPSIP Block to Help Pain After Breast Reduction Surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective, randomized, assessor-blinded study compares standard anesthesia and pain care with or without a bilateral SPSIP block in adults undergoing reduction mammaplasty. All participants receive routine surgical local infiltration and postoperative pain management, and pain scores and analgesic use are tracked for 24 hours. The study also monitors safety and complications for 30 days. It is conducted at a single center and aims to see if the SPSIP block provides additional opioid-sparing benefit beyond standard care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Female participants aged 18 to 65 years
* Scheduled for elective bilateral reduction mammaplasty
* Planned surgery under general anesthesia
* American Society of Anesthesiologists physical status class I to III
* Planned postoperative clinical follow-up for the first 24 hours after surgery
* Able to understand and report pain using the 0 to 10 Numeric Rating Scale
* Able to provide written informed consent for study participation

Exclusion Criteria:

* Known allergy or hypersensitivity to local anesthetic drugs
* Contraindication to regional anesthesia or fascial plane block
* Coagulopathy or clinically significant bleeding disorder
* Use of anticoagulant or antiplatelet medication that prevents safe block application
* Infection at the planned block injection site
* Chronic opioid use, chronic pain syndrome, or regular analgesic use that may affect postoperative pain assessment
* Revision breast surgery
* Planned major additional surgical procedure other than reduction mammaplasty
* Pregnancy or lactation
* Unable to reliably report pain scores

Where it's running

• Sivas Cumhuriyet University
  Sivas, Sivas, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Murat Çelik, Assistant Professor
• Email: mucetr@gmail.com
• Phone: +905546902104

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Comparing two nerve block techniques for pain relief after hip surgery

  This study is testing which of two nerve block techniques helps people recover with less pain and fewer opioids after hip surgery.

  Recruiting Başakşehir Çam & Sakura City Hospital · Istanbul, Türki̇ye · NCT06821516

• Using remote guidance to improve regional anesthesia training

  This study tests whether using real-time remote guidance from expert anesthesiologists can help train doctors in ultrasound-guided regional anesthesia techniques to improve patient safety and satisfaction.

  Recruiting Queen's University · Kingston, Ontario · NCT05968261

• Anterior Knee Nerves Block vs Femoral Nerve Block for Knee Arthroscopy

  This trial tests whether an anterior nerves of the knee (ANK) block provides similar pain relief to a femoral nerve block after knee arthroscopy in adults, aiming to reduce quadriceps weakness.

  Recruiting Van Training and Research Hospital · Van · NCT07910500

• Suzetrigine for pain relief after knee replacement

  This trial tests whether suzetrigine can reduce opioid use after a total knee replacement compared with placebo.

  Recruiting Phase 3 Hospital for Special Surgery, New York · New York, New York · NCT07864896

• Esmolol vs Dexmedetomidine for opioid-sparing in laparoscopic gynecologic surgery

  This study tests whether low-dose esmolol or dexmedetomidine, given during surgery, reduces opioid use and improves pain control after laparoscopic hysterectomy compared with placebo.

  Recruiting National and Kapodistrian University of Athens · Athens · NCT07846722

• Three nerve blocks for knee replacement: which one works best

  This trial tests three different nerve blocks used during knee replacement to see which provides the best pain relief for patients after surgery.

  Recruiting I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio · Milan, Italy and 1 other locations · NCT07751653

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.