Sponsor or institution
Clinical trials and research at West Virginia University
As of November 12, 2026, Find a Trial lists 21 clinical trials run by West Virginia University that are recruiting, in United States. By phase: Phase 1/2 (3), Phase 2 (3), Phase 1 (2), Early Phase 1 (1). There are also 153 NIH-funded research projects at this institution, with $86.7 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 21Clinical trials
- 153NIH research projects
- 1Country
Newest trials
All recruiting trials (21)
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ENLIGHT: Adding fundal mucosal ablation to endoscopic sleeve gastrostomy for obesity
This trial tests whether adding fundal mucosal ablation to endoscopic sleeve gastroplasty helps adults with obesity lose more weight and improve metabolic health compared with ESG alone.
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EUS-Guided Ablation for Pancreatic and GI Lesions Registry
This registry collects real-world data on adults undergoing EUS-guided RFA or MWA to treat pancreatic or other GI lesions during routine care to see how these treatments affect lesion size, survival, and symptoms.
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5% 5‑fluorouracil with or without 15% aluminum chloride for actinic keratoses
This will see if adding 15% aluminum chloride to 5% 5‑fluorouracil cream helps clear actinic keratoses on the scalp or forearms in adults with 4–15 lesions after one week of treatment.
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Rapid HIV, HCV, and syphilis screening at a rural street-medicine clinic
A rapid fingerstick test is being tested in a mobile street-medicine clinic to see if it increases uptake and quick linkage to care for HIV, HCV, and syphilis among adults served by WVU Street Medicine.
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Subcutaneous blinatumomab treatment for adults with CD19-positive mixed phenotype acute leukemia
This trial tests whether giving blinatumomab under the skin can help adults with CD19-positive mixed phenotype acute leukemia, including older or unfit newly diagnosed patients, those with measurable residual disease after remission, and those with relapsed or refractory disease.
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Lifting More Than Weights: a resistance exercise program to reduce fatigue after breast cancer across socioeconomic groups
This project will try a tailored resistance exercise program to see if it helps reduce fatigue and improve readiness to exercise in Appalachian breast cancer survivors from different socioeconomic backgrounds.
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Leflunomide plus decitabine for relapsed or refractory myelodysplastic syndromes
This study will test whether adding the oral drug leflunomide to IV decitabine is safe and tolerable for adults with relapsed or refractory MDS who have already received a hypomethylating agent.
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Treatment of lipomas with cooled sodium chloride injections
This study is testing if cooled saltwater injections can shrink lipomas, which are harmless fat lumps, as a non-surgical option for people looking for cosmetic improvement or symptom relief.
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Evaluating a suicide risk screening program in rural schools
This study is testing a new program in rural West Virginia schools to see if it can help identify and support students at risk of suicide.
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Home palliative care for heart failure patients in rural Appalachia
This study tests a new home care program for families taking care of loved ones with advanced heart failure in rural Appalachia to see if it improves their quality of life and reduces stress over a year.
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Investigating how cannabidiol affects driving performance in healthy adults
This study is testing how different doses of CBD oil affect driving performance and alertness in healthy adults aged 18-30.
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Using rTMS to treat impulse control disorders in Parkinson's disease
This study is testing if a treatment called rTMS can help people with Parkinson's disease who struggle with impulse control issues feel more in control of their behaviors.
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Using brain stimulation and thinking strategies to reduce smoking cravings
This study is trying to see if using brain stimulation along with different thinking strategies can help moderate to heavy smokers feel less craving for cigarettes when they look at smoking-related images.
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Using focused ultrasound to treat severe opioid use disorder
This study is testing whether low intensity focused ultrasound can help people aged 22 to 60 with severe opioid use disorder who haven't had success with other treatments.
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Using low-intensity focused ultrasound to treat mild cognitive impairment in Alzheimer's patients
This study is testing if low-intensity focused ultrasound can safely help people with mild cognitive impairment from Alzheimer's feel better.
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Using TMS to enhance behavioral therapy for Tourette Syndrome
This study is testing if adding a brain stimulation treatment to behavioral therapy can help adults with Tourette Syndrome reduce their tics more effectively.
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Using Xerava to prevent infections in patients with blood cancers and low white blood cell counts
This study is testing if the antibiotic Xerava can help prevent infections in patients with blood cancers who have low white blood cell counts during their treatment.
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Using heated chemotherapy to treat high-risk gallbladder cancer
This study is testing a new heated chemotherapy treatment for people with high-risk gallbladder cancer to see if it can help them fight difficult-to-treat tumors.
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Using pioglitazone to reduce fatigue in breast cancer patients
This study is testing if the diabetes drug pioglitazone can help reduce muscle fatigue in breast cancer patients who haven't started treatment yet.
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Combination of chemotherapy and hydroxychloroquine for pancreatic cancer treatment
This study is testing if combining a specific chemotherapy with hydroxychloroquine can help people with pancreatic cancer have better surgery results and improve their overall health.
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Blocking blue light at night to improve recovery after heart surgery
This study tests if wearing blue light-blocking goggles at night can help people recovering from heart surgery feel better and heal faster.
NIH-funded research (newest 40 of 153)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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West Virginia Rural Roots to Research: bringing clinical trials to Appalachian communities
A wide-network program in rural West Virginia is building patient-friendly clinical trials so people in Appalachia have better access to new cancer treatments and care.
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CD38-Driven Changes in Brain Tumor Metabolism and Immunity in Glioblastoma
A patient-facing look at how scientists plan to study how glioblastoma grows by changing its metabolism and dampening the immune response, with potential targets to help treatment in the future.
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Combinatorial targeting for high-risk B-cell ALL treatment
A research effort at West Virginia University is exploring a combination therapy for adult B-cell acute lymphoblastic leukemia using targeted gene silencing and a small-molecule compound to improve treatment in patients.
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New mRNA vaccines and antibody therapies to prevent and treat pertussis
A program to create and test new mRNA vaccines and antibody therapies to stop whooping cough from spreading and causing illness in people of all ages.
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Targeting teens’ social media use and real-time chats to improve well-being
A teen-focused program tests whether reducing social media, boosting real-time conversations, or journaling can improve well-being in 10th graders.
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Molecular Regulators of Cone Opsin Trafficking
A study to understand how light-sensitive cone proteins are moved to the part of the eye that detects light, with the goal of helping people with certain inherited eye diseases.
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Musculoskeletal tissue damage linked to prosthetic joint infection and a new protective drug
A study in rats will test whether a new drug can protect bone and muscle from damage caused by prosthetic joint infection.
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Improving MRI to better detect remaining breast cancer after chemotherapy
A new MRI contrast agent called NEMO is being developed to more accurately show where breast cancer remains after chemotherapy, potentially reducing unnecessary mastectomies.
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Ligand Specificity and Activation of Receptor Guanylyl Cyclases
This NIH grant supports research to understand how receptor guanylyl cyclases (rGCs) work and how their activation affects important body processes and diseases.
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Metabolic changes in pancreatic cancer when treated with crisantaspase
Aims to understand how pancreatic cancer cells adapt their metabolism when treated with crisantaspase to inform better treatment strategies for patients.
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TP53-mutant NSCLC: how epigenetic viral mimicry could boost immune therapy
A research grant exploring how p53 mutations in non-small cell lung cancer affect responses to a viral mimicry-based epigenetic therapy, with the goal of improving immune therapy outcomes for patients.
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Flow Cytometry and Single-Cell Analysis Core for Biomedical Research
A core facility at West Virginia University provides advanced flow cytometry and single-cell technologies to support cancer-related research and other biomedical projects.
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Imaging Core for Cancer Research at WVU
A funded Imaging Core at West Virginia University supports animal and cellular cancer research by providing advanced imaging tools and training.
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Tumor microenvironment research hub to advance cancer care in Appalachia
A cancer-focused research center at West Virginia University is exploring how the tumor environment affects cancer progression and therapy, with a goal of improving care for people in Appalachia.
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Clinical Research Resources and Facilities Core to boost rural participation in WV clinical trials
A program to build and connect clinical research facilities in West Virginia so rural patients can join high-quality clinical trials.
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Technologies and Resources that Power Core Lab Work
A core facility grant that helps West Virginia researchers access advanced lab tools and training to speed up cancer-related discoveries for patients in West Virginia.
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Tracking and Evaluation Core for WV CTSA
A core team at WVU helps other research cores track progress and use data to improve how they work.
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Pilot Projects Program for West Virginia clinicians and researchers
A small, flexible grant program helps early-career researchers in West Virginia kick off clinical and translational projects that could improve local health.
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Community Engagement and Outreach Core supports West Virginia research with patients and providers
A program core at WVU works with patients and communities to shape research priorities and make study results useful for local health improvements.
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Biostatistics and Data Design Support for West Virginia Researchers
This grant funds a BERD core to help West Virginia researchers with statistics, study design, and data tools to improve health research outcomes.
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Professional Development Core for Clinical and Translational Scientists
A program that helps clinicians and researchers in West Virginia build and sustain independent CTS research careers through mentoring, workshops, and grant support.
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Administrative Core for WV Clinical and Translational Science Institute
This grant funds a central administrative core to keep West Virginia’s clinical and translational research programs organized, collaborative, and accountable.
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West Virginia CTSI: Building Health Research and Engaging Communities Across the State
A statewide program in West Virginia is funded to build research infrastructure, train scientists, and engage communities to improve health outcomes.
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ICE Collaborative: A community-led approach to preventing adolescent substance use in rural America
A nationwide study will test a community-driven prevention approach to reduce substance use among rural adolescents by strengthening local coalitions and adapting proven programs to fit local needs.
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Increasing access toclinical trials in IDAE states through better communication, marketing, and workforce development
A national program aims to help people in IDA states learn about and participate in more clinical trials by improving communication with sponsors, marketing opportunities, and training trial staff.
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West Virginia Pediatric Clinical Trials Network: Expanding Kids’ Access to Clinical Studies
A dedicated pediatric clinical trials network in West Virginia is expanding access for children with chronic conditions by bringing trials to local hospitals and building research capacity.
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How zinc at brain synapses shapes thinking and behavior in autism
This grant explores how zinc released at brain connections influences brain signaling and may relate to autism-related brain changes.
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Understanding how a key glycolysis enzyme is controlled in cells and its role in cancer and neurodegeneration
A research project will study how the enzyme PFK1, a regulator of glucose metabolism, is controlled in liver cells and how this affects breast cancer cell movement and disease-related metabolism.
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Role of IPM Proteoglycans in Retinal Health and Inherited Blindness
This grant studies how specific retinal extracellular matrix proteins (IMPG1 and IMPG2) affect eye health and contribute to retinitis pigmentosa, with potential implications for people who have or are at risk for inherited blindness.
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mitoNEET protein as a target to reduce brain damage after stroke
A new treatment approach targets a mitochondrial protein called mitoNEET to limit brain injury after a stroke by improving energy use and protecting vulnerable brain cells.
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Bringing clinical trials to rural West Virginia
This project will set up a network to bring more clinical trials closer to people living in rural West Virginia, including those with cancer and other chronic health problems.
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NMNAT1’s role in protecting retinal cells and guiding gene therapies for inherited blindness
A patient-focused look at how NMNAT1 supports retinal light-sensing cells and how new therapies might prevent early blindness in Leber congenital amaurosis.
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Sustaining at-Home Heart Failure Care for Older Adults in Rural Appalachia
A team at West Virginia University is testing a nurse-led program to support older adults with heart failure and their families at home in rural Appalachia to reduce hospital visits and improve comfort.
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How tire and road wear particles affect healthy and inflamed lungs
This grant studies how tire and road wear particles may harm the lungs, especially when inflammation is already present, to help protect people who breathe polluted air.
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NIMH Clinical Pathway for Suicide Prevention in Rural Appalachian Schools
A pilot project to adapt and test a proven suicide-risk pathway in two rural Appalachian school health centers to help mix in screening, quick assessment, and follow-up for youth.
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Nanogel-enabled Glycosylation Analysis at the Nanoscale
Aims to develop tiny, biocompatible nanogel methods to study glycosylation patterns, especially sialylation, in biochemical samples using advanced capillary electrophoresis.
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AURKA/KAP1 signals linked to breast cancer spread
A doctor-research team is studying how a protein called AURKA, and its partner KAP1, may drive early spread of aggressive breast cancer by changing how cancer cells read their genes.
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Redox-epigenetics and vascular stiffness in obesity-related heart disease
Aimed at understanding how redox signals and epigenetic changes drive stiff blood vessels in adults with obesity, to improve cardiovascular health.
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Role of LonP1 in protecting the heart from ischemia-reperfusion injury
A study to see if boosting a mitochondrial protein called LonP1 can reduce heart damage after a blocked artery is opened in people who have a heart attack.
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CBD and how it affects driving in healthy adults
A 3-arm randomized study will examine how different doses of cannabidiol (CBD) influence driving performance and alertness in healthy adults.
Quick answers
How many clinical trials run by West Virginia University are recruiting right now?
21, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
All of them have sites in United States. Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1/2: 3, Phase 2: 3, Phase 1: 2, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.