NIH-funded research R01 grant

Sustaining at-Home Heart Failure Care for Older Adults in Rural Appalachia

Official title: Sustaining Home Palliative Care for Patients with Heart Failure (HF) and Their Family Caregivers in Rural Appalachia: A Mixed Methods Randomized Clinical Trial (RCT)

Funded at West Virginia University · NIH-11367982 · Data updated 2026-11-12

A team at West Virginia University is testing a nurse-led program to support older adults with heart failure and their families at home in rural Appalachia to reduce hospital visits and improve comfort.

More Heart Failure research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWest Virginia University
NIH-funded
Lab location1 site (Morgantown, United States)
Project startSeptember 19, 2024
Project endMay 31, 2028
Funding year2026
Award (this year)$701,532
NIH project number5R01NR021630-03
Project IDNIH-11367982 on NIH RePORTER

Who could benefit from this research

Could help

Older adults (65+) with heart failure and their family caregivers living in rural Appalachia who have limited access to specialty palliative care.

Less likely to help

Patients who do not receive the bundled intervention or who have conditions requiring more intensive, facility-based care may not benefit.

What this research studies

This project tests a combined home-care approach for seniors with heart failure living in rural Appalachia, using nurse-led support, home-care resources, and faith-based community connections. The study uses a randomized design to compare the new bundled care against standard care, with components designed to improve access to services, caregiver support, and safe, comfortable end-of-life care. Participants include patients age 65 and older and their family caregivers, guided by Appalachian cultural strengths and social support theory. The goal is to make home management of heart failure more feasible and less burdensome for families in a region with limited health resources.

Why it matters

Potential benefit: If successful, patients and families could experience better symptom control, fewer hospitalizations, and greater peace of mind at home.

How similar studies have gone: Previous components showed promise, and the mixed-methods RCT will test combined approaches in a real-world rural setting.

Where this research is happening

  • West Virginia University
    Morgantown, United States
    Active

Researchers

  • Principal investigator: Piamjariyakul, Ubolrat — West Virginia University
  • Study coordinator: Piamjariyakul, Ubolrat

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.