Treatment of lipomas with cooled sodium chloride injections
Lipomas Treated With Subcutaneous Injections of Cooled or Warmed Sodium Chloride: an Exploratory Study
This study is testing if cooled saltwater injections can shrink lipomas, which are harmless fat lumps, as a non-surgical option for people looking for cosmetic improvement or symptom relief.
Quick facts
| Phase | Phase1; Phase2 |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | West Virginia University Academic / other |
| Locations | 1 site (Morgantown, West Virginia) |
| Trial ID | NCT06820164 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of subcutaneous injections of cooled normal saline as a treatment for lipomas, which are benign tumors made of fat tissue. The approach aims to provide a non-surgical alternative to existing treatments, particularly for patients seeking cosmetic improvement or relief from symptoms caused by lipomas. The study will compare this method to traditional fat-freezing devices, assessing comfort and efficacy in reducing lipoma size. Participants will receive injections directly into their lipomas to determine if this technique can effectively reduce their presence.
Who should consider this trial
Good fit: Ideal candidates are individuals with at least one clinically diagnosed subcutaneous lipoma who meet the inclusion criteria.
Not a fit: Patients with lipomas on the face, larger than 10 cm, or those exhibiting rapid growth or abnormal ultrasound findings may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could offer a more comfortable and non-invasive option for patients seeking to reduce or eliminate lipomas.
How similar studies have performed: While this approach is exploratory, similar non-surgical methods for fat reduction have shown promise in other studies, though this specific technique is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * At least one clinically diagnosed subcutaneous lipoma Exclusion Criteria: * Unable to give informed consent * Participant has a lipoma on the face * Lipomas located subfascial or within deep tissue (e.g., intramuscular lipomas) * Lipomas larger than 10 cm in diameter (fat deposits exceeding 500 mL in volume) * Rapidly growing lipomas * Lipomas exhibiting abnormal ultrasound findings (e.g., complex hyperechoic patterns, internal heterogeneity, or multilobulated appearance) * Pregnant women
Where this trial is running
Morgantown, West Virginia
- West Virginia University — Morgantown, West Virginia, United States (Recruiting)
Study contacts
- Principal investigator: Jessica Patterson, MD — West Virginia University-Dermatology
- Study coordinator: Jessica Patterson, MD
- Email: jpatter5@hsc.wvu.edu
- Phone: 304-598-4865
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.