Blocking blue light at night to improve recovery after heart surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates whether filtering out blue light at night can reduce inflammation and improve cognitive function, mood, and sleep in patients recovering from elective heart surgeries such as CABG, AVR, and MVR. The approach involves using blue light-blocking goggles during the night to create a more conducive recovery environment. The hypothesis is based on previous animal studies suggesting that exposure to blue light can exacerbate inflammation and cognitive decline post-surgery. If successful, this intervention could lead to shorter hospital stays and improved patient outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Both men and women that are undergoing elective (non-emergency)

  * on-pump CABG surgery,
  * AVR,
  * MVR,
  * CABG AVR,
  * CABG MVR or
  * SAH
* No history of diagnosed psychiatric disorders or organ failure

Exclusion Criteria:

* Evidence or diagnosis of dementia or other cognitive deficit
* Diagnosed psychiatric disorder (including depression and anxiety)
* Organ failure \[kidney (creatine \> 1.5 mg/dL), liver, etc.\]
* Chronic obstructive pulmonary disease,
* Any immune disorder
* Acute infection
* Prior cardiac surgery
* Elective aneurysms
* Combined cardiac operations
* Left main stenosis greater than 70%
* Left ventricular ejection fraction (LVEF) lower than 0.5
* Any condition that increases likelihood of the need for a blood transfusion during or after the surgery
* Clotting disorder
* Suspected less than 8th grade English reading comprehension level

Where it's running

• West Virginia University Heart and Vascular Institute
  Morgantown, West Virginia, United States Recruiting

Study contacts

• Principal investigator: Randy J Nelson, PhD — West Virginia University
• Study coordinator: James C Walton, PhD
• Email: james.walton@hsc.wvu.edu
• Phone: 3042933490

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.