Using TMS to enhance behavioral therapy for Tourette Syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot study investigates the effects of repetitive transcranial magnetic stimulation (rTMS) combined with comprehensive behavioral intervention for tics (CBIT) in adults with Tourette Syndrome. Participants with moderate tic severity will be randomly assigned to receive either active or sham rTMS targeting the supplementary motor area, followed by eight sessions of CBIT. The study aims to measure changes in tic frequency and severity, as well as neurophysiological changes, comparing outcomes between the two groups. The hypothesis is that rTMS will enhance the effectiveness of CBIT by positively influencing the SMA network.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 years or older
* Diagnosis of Tourette Syndrome
* Moderate Tic Severity at baseline

Exclusion Criteria:

* Presence of metallic objects or neurostimulators in the brain
* Pregnancy
* History of active seizures or epilepsy
* Contraindications to receiving fMRI
* Inability to participate in CBIT due to other underlying cognitive or medical condition

Where it's running

• Wvu Rni
  Morgantown, West Virginia, United States Recruiting

Study contacts

• Principal investigator: Jessica Frey, MD — Wvu Rni
• Study coordinator: Jessica Frey, MD
• Email: Jessica.frey@hsc.wvu.edu
• Phone: 304-598-6127

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Understanding changes in Tourette Syndrome

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.