NIH-funded research R01 grant

ICE Collaborative: A community-led approach to preventing adolescent substance use in rural America

Official title: Shifting the Landscape in Primary Substance Use Prevention for Rural America: The Integrated Community Engagement (ICE) Collaborative Cluster Trial

Funded at West Virginia University · NIH-11400494 · Data updated 2026-11-12

A nationwide study will test a community-driven prevention approach to reduce substance use among rural adolescents by strengthening local coalitions and adapting proven programs to fit local needs.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWest Virginia University
NIH-funded
Lab location1 site (Morgantown, United States)
Project startSeptember 1, 2025
Project endJuly 31, 2030
Funding year2026
Award (this year)$1,379,830
NIH project number5R01DA063662-02
Project IDNIH-11400494 on NIH RePORTER

Who could benefit from this research

Could help

Adolescents aged 10–21 living in rural communities in the United States, and the caregivers and local stakeholders involved in prevention efforts.

Less likely to help

Communities lacking capacity-building resources or willingness to adopt local, coalition-based approaches may see limited benefit.

What this research studies

This project partners with rural communities to build prevention capacity and support for evidence-based programs. It adapts a successful Icelandic model to fit local values, resources, and priorities, emphasizing local decision making and sustainability. The study uses coalition-based strategies to improve how prevention programs are chosen, implemented, and guided by data from multiple community stakeholders. Through iterative testing, it aims to create a flexible, principle-based implementation framework that can be applied in diverse rural settings.

Why it matters

Potential benefit: If successful, communities could sustain effective prevention efforts that reduce early substance use among rural youth.

How similar studies have gone: Previous randomized trials show efficacy of EBIs, but there are few scalable implementations in rural settings; this study extends that work with a community-centered adaptation.

Where this research is happening

  • West Virginia University
    Morgantown, United States
    Active

Researchers

  • Principal investigator: Kristjansson, Alfgeir — West Virginia University
  • Study coordinator: Kristjansson, Alfgeir

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.