Sponsor or institution
Clinical trials and research at University of Michigan at Ann Arbor
As of November 12, 2026, Find a Trial lists 2,634 NIH-funded research projects at this institution, with $1.6 billion in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 2634NIH research projects
NIH-funded research (newest 40 of 2634)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Expanding genetic testing for cancer risk in patients and families
This study is working to make it easier for cancer patients in Michigan to get genetic testing for cancer risk by improving how doctors gather family history and assess genetic risks, so that more people can receive the important evaluations they need.
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HEARTS hypertension and diabetes care in Guatemala
This grant tests how well the HEARTS primary care model works in Guatemala to improve blood pressure and blood sugar control for patients.
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Why the retina can sometimes heal itself and how we might help it heal
This NIH grant explores how inflammation and neural cells interact in the zebrafish retina to understand retinal neuron death and regeneration, with potential implications for human vision.
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Integrated Heart Health: A HEARTS-based approach to hypertension and diabetes in Guatemala
A study tests a team-based, stepwise care model to improve blood pressure and blood sugar control for people with both hypertension and diabetes in Guatemala.
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Understanding how work exposures and genes influence ALS risk
A study is building a long-term group of people at higher risk for ALS to see how their jobs, exposures at work, and genes together affect if and when the disease might develop.
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An integrated mobile health program to reduce SAVA and mental health problems among female sex workers in Kenya
A new mobile health program aims to help female sex workers in Kenya avoid substance abuse, violence, HIV, and depression by delivering group therapy, online resources, and a peer discussion space.
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Youth gun-violence prevention for urban teens
A nationwide study from the University of Michigan is testing proven violence-prevention programs to reduce firearm injuries and deaths among urban youth aged 14–20.
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Postoperative Pain Guidelines for Pregnancy: Safer, Patient-Centered Opioid Use
We’re creating patient-friendly guidelines to help doctors manage pain after delivery and surgery in pregnant people, aiming to reduce opioid overuse and improve safety.
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Biological aging across the lifespan through a national high school-to-adult study
This grant uses a long-running national study of students and adults to collect saliva biomarkers of aging, alongside surveys, to understand how aging markers relate to health and life experiences.
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Understanding what people value about vaccines to improve vaccination policy and uptake
A payer/policy-focused project uses surveys to learn what matters to people about vaccines so decisions can help more people get vaccinated.
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Skeletal stem cell and immune cell dynamics in BMP-2 assisted cleft palate repair
A study explores how bone-building stem cells and immune cells interact to improve bone repair in cleft palate patients using BMP-2, aiming for a less invasive option than bone grafts.
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PanKbase: a shared hub for pancreas data and insights
A national project will bring together diverse pancreas and islet data to create an accessible, connected knowledgebase to help people with brittle diabetes and related conditions.
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National Neighborhood Data Archive helps researchers study aging health in U.S. neighborhoods
A nationwide data resource will help researchers understand how where people live affects health and aging, with a focus on respiratory illnesses in older adults.
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Autophagy's role in enamel development explained for your teeth
A short study will explore how autophagy affects the cells that form enamel, aiming to understand why some people have enamel defects.
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Smartphone app helps pregnant women in Ghana monitor blood pressure at home
A smartphone app is being customized for pregnant women in Ghana to support home blood pressure monitoring and improve safety during pregnancy.
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Understanding TDP43 Mislocalization in Aging and ALS-FTLD-LATE
Researchers are studying how the TDP43 protein misfolds and clumps in aging brains, to help people with ALS and related disorders.
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Understanding how to use pharmacogenomic testing to guide chronic pain care
This grant looks at how doctors who treat long‑term pain decide when and how to use genetic testing to tailor pain medicines for safer and more effective care.
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Understanding how specific brain proteins affect autism-related brain activity
Researchers are studying how particular brain proteins called NaV channels and ankyrins influence neuron signaling in autism-related conditions.
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Mitochondrial therapy after brain injury to protect the brain
Aims to see if a light-based therapy given after brain injury can protect brain cells and reduce damage.
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Understanding how heart energy and pumping power limit exercise in healthy people and heart failure
A research project using computer models to study how heart energy and pumping strength, plus blood vessel and nervous system factors, limit exercise capacity in healthy adults and people with heart failure.
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Statin therapy for people with compensated cirrhosis
A big, long-term study at a major university is looking at whether statins can help people with compensated cirrhosis live longer and feel better.
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Intergenerational factors in neurodevelopmental disorders
This project looks at how experiences before and during pregnancy across generations may influence the risk of neurodevelopmental conditions like ADHD, autism, and related disorders in grandchildren.
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Nanol therapies to target corneal blood vessel growth
A tiny, targeted treatment approach aims to stop new blood vessels from growing into the cornea to protect vision.
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Deciphering how perforin helps T cells kill cancer through ferroptosis
This grant explores how a T cell protein called perforin might trigger a special kind of cancer cell death called ferroptosis to boost anti-tumor immunity.
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Contraceptive decision support tool for postpartum women and child outcomes
A tablet-based decision tool helps postpartum women in Ghana choose contraception that fits their preferences, and follows families for two years to see how choices affect mothers and babies.
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Zoonotic UPEC in Northwest Ecuador: Who gets UTIs and how it spreads
Researchers will explore how uro-pathogenic E. coli from animals and the environment may cause UTIs in people in Northwest Ecuador.
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How chromosomes move during mammalian meiosis
This project studies how chromosomes move in germ cells during meiosis to learn why errors can lead to infertility or miscarriage.
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Co-designing a multimodal AI system to map T1D progression
A team at the University of Michigan is building an AI-powered system to combine multiple types of diabetes data to reveal how Type 1 Diabetes progresses.
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Personalized immunomodulation for septic children in critical care
A national network is testing tailored treatments for kids with sepsis-related organ failure to see if personalized care improves outcomes.
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VIOLIN 2.0: A vaccine knowledgebase to speed safe vaccines
A project to build VIOLIN 2.0, a user-friendly vaccine information and ontology knowledgebase to help researchers develop safer, more effective vaccines for diseases like HIV, TB, and malaria.
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Longitudinal health and aging study in Kenya
A large, long-term study in Kenya will track health, well-being, economics, and aging in adults 45 and older to understand rising aging needs and risk factors for dementia.
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Programs and policies to prevent child sexual abuse
This project compares programs and policies meant to prevent child sexual abuse and protect children and families.
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Harmonized, cross-site fMRI platform to compare brain activity across hospitals
A nationwide effort to build a shared, vendor-agnostic fMRI system so researchers can collect and compare brain imaging data reliably across many centers, helping people with brain-related conditions.
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Best practices for sharing aging data to speed dementia research
This grant improves a nationwide aging data resource so researchers can more easily share and reuse information about aging and Alzheimer’s-related conditions.
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MiCAS: Chemical Analysis of MoTrPAC Samples to Understand Body Fat and Blood Health
This NIH grant supports advanced chemical analysis of samples from people in the MoTrPAC program to learn how physical activity affects fat, blood, and muscle at the molecular level.
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Coordinating Center for Social, Behavioral, and Economic Research on Public Health Emergencies
A national collaboration hub helps researchers study how social, behavioral, and economic factors affect public health emergencies using shared data resources.
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Biomolecule Modeling Tools and Software for Cancer Research
Aims to develop and test computer-based tools to study how biomolecules interact, helping cancer researchers better understand how molecules bind and work.
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Indigenized Family Acceptance Project for Lakota LGBTQ2S+ Youth
A culturally tailored program helps Lakota LGBTQ2S+ teens (ages 13–18) and their caregivers feel safer, connected, and supported at home and in their community.
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Integrative multi-omics to understand diabetic retinopathy
A doctor-scientist team will study blood markers and genetic signals to see why diabetic retinopathy happens and how it affects Hispanic/Latino people.
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Biobank tools to better understand and manage eye diseases
A study to connect eye disease genetics with real-world health data to improve understanding and care for eye conditions.
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