Understanding how to use pharmacogenomic testing to guide chronic pain care
Official title: Understanding barriers and facilitators to pharmacogenomic testing in chronic pain care
Funded at University of Michigan at Ann Arbor · NIH-11602241 · Data updated 2026-11-12
This grant looks at how doctors who treat long‑term pain decide when and how to use genetic testing to tailor pain medicines for safer and more effective care.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | August 25, 2026 |
| Project end | July 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $247,039 |
| NIH project number | 4R00HG013600-03 |
| Project ID | NIH-11602241 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with chronic pain who require analgesics and may benefit from pharmacogenomic-guided prescribing.
✕Less likely to help
Patients unlikely to benefit include those not receiving pharmacogenomic testing or those whose pain management does not involve genetic-informed decisions.
What this research studies
Chronic pain patients often receive medications that work differently from person to person. This project explores why pharmacogenomic testing is not widely used in pain management and what clinical and ethical factors influence its use. Using mixed methods, it will study pain physicians’ knowledge, attitudes, and practices to identify barriers and opportunities to integrate genetic testing into routine care. The goal is to make genomic information more accessible so that treatments can be safer and more effective for patients with chronic pain. The work is conducted within a five-year training and research plan at the University of Michigan under the K99/R00 mechanism.
Why it matters
Potential benefit: If successful, patients with chronic pain could receive more personalized and safer pain medications guided by genetic information.
How similar studies have gone: Previous work has shown varying adoption of pharmacogenomic testing across specialties; this project addresses gaps specific to pain medicine and education.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Hendy, Katherine Marie — University of Michigan at Ann Arbor
- Study coordinator: Hendy, Katherine Marie
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.