Biobank tools to better understand and manage eye diseases
Official title: Biobank phenotyping tools for improved understanding and management of eye diseases and disparities
Funded at University of Michigan at Ann Arbor · NIH-11513632 · Data updated 2026-11-12
A study to connect eye disease genetics with real-world health data to improve understanding and care for eye conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | March 20, 2026 |
| Project end | April 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $437,501 |
| NIH project number | 7R01EY036473-03 |
| Project ID | NIH-11513632 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are individuals with eye conditions whose health data and biospecimens are part of biobank or EHR-linked research resources, especially where ancestry or demographic factors may influence disease patterns.
✕Less likely to help
Individuals without eye disease or without access to linked health records or biospecimens may not directly benefit.
What this research studies
This project uses biobank samples and electronic health records to link genetic data with patient health information focused on eye diseases. Researchers will refine phenotyping tools (phecodes) to better capture eye-related health patterns and disease mechanisms. The goal is to improve risk prediction and identify new directions for treatment and management of eye diseases, including disparities among different populations. The work involves data integration, development of pipelines, and collaboration with clinical partners to translate findings into practical insights. The project runs from 2026 to 2029 at the University of Michigan and will involve analysis of human health data and biospecimens relevant to eye conditions.
Why it matters
Potential benefit: If successful, patients could see improved risk prediction and personalized management of eye diseases based on integrated genetic and health data.
How similar studies have gone: Previous work with phecodes and phenotype-genotype linkage has advanced understanding, but current limitations in resolution for certain sight-threatening conditions remain a challenge.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Padovani-Claudio, Dolly Ann — University of Michigan at Ann Arbor
- Study coordinator: Padovani-Claudio, Dolly Ann
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.