NIH-funded research NIH-funded research

MiCAS: Chemical Analysis of MoTrPAC Samples to Understand Body Fat and Blood Health

Official title: Michigan MoTrPAC Chemical Analysis Site (MiCAS)

Funded at University of Michigan at Ann Arbor · NIH-11528824 · Data updated 2026-11-12

This NIH grant supports advanced chemical analysis of samples from people in the MoTrPAC program to learn how physical activity affects fat, blood, and muscle at the molecular level.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor
NIH-funded
Lab location1 site (Ann Arbor, United States)
Project startDecember 8, 2016
Project endMay 31, 2027
Funding year2026
Award (this year)$1,421,363
NIH project number3U24DK112342-08S1
Project IDNIH-11528824 on NIH RePORTER

Who could benefit from this research

Could help

Individuals whose samples are part of the MoTrPAC study, including those who provided blood, muscle, or adipose tissue, may be relevant for related analyses.

Less likely to help

This grant involves analysis of existing samples and does not involve direct patient care or treatment in participants.

What this research studies

The project aims to perform extensive metabolomics analysis on thousands of samples from blood, muscle, and adipose tissue using multiple mass spectrometry platforms. Data will be processed with an established pipeline and shared with the Stanford Bioinformatics Center to build a clearer picture of how physical activity impacts metabolism. This work could help translate findings about how exercise changes body chemistry into strategies to improve health and prevent disease. Participation would mainly involve providing biological samples from study participants and does not require any direct patient intervention.

Why it matters

Potential benefit: If successful, the research could reveal molecular fingerprints of physical activity that inform personalized health recommendations.

How similar studies have gone: Previous MoTrPAC analyses have demonstrated meaningful links between activity and metabolic changes, supporting the potential for impactful discoveries here.

Where this research is happening

  • University of Michigan at Ann Arbor
    Ann Arbor, United States
    Active

Researchers

  • Principal investigator: Burant, Charles F — University of Michigan at Ann Arbor
  • Study coordinator: Burant, Charles F

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.