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Clinical trials and research at Shanghai Jiao Tong University School of Medicine

• 60Clinical trials
• 2New in 30 days
• 1Country

Newest trials

All recruiting trials (60)

• FM Move: A New Method for Moving Back Teeth During Clear Aligner Therapy

  A single-group study tests a new FM method to move the canine and first molar together in people needing back-teeth movement, to see if treatment time can be shortened.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai · NCT07896369

• Sitogilun Malate with Amlodipine in High Blood Pressure with Early Kidney Risk

  This trial tests whether sitogilun malate plus amlodipine helps lower blood pressure in adults with mild-to-moderate hypertension and early signs of kidney stress.

  Recruiting Phase 4 Shanghai Jiao Tong University School of Medicine · Shanghai, China · NCT07876544

• Active safety and performance monitoring of a biodegradable PFO closure device and a transcatheter mitral valve repair system

  This study tracks how well a biodegradable PFO closure device and a transcatheter mitral valve repair system work and stay safe when used in routine care.

  Recruiting at 3 sites Shanghai Jiao Tong University School of Medicine · Lanzhou, Gansu and 10 other locations · NCT07848152

• AI-powered personalized exercise coaching for women with breast cancer

  This trial tests whether an AI-driven, personalized exercise program helps women with breast cancer after treatment compared to standard exercise guidance.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT07844941

• Oral health, saliva bacteria, and disease activity in children with JIA

  This study checks if how active juvenile idiopathic arthritis is relates to oral health in children who already receive rheumatology care.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai, Pudongxinqu · NCT07799831

• Neoadjuvant Pyrotinib-to-pertuzumab for HER2-positive early breast cancer

  This trial tests whether a two-step neoadjuvant plan with Pyrotinib plus Trastuzumab and Docetaxel followed by Pertuzumab plus Trastuzumab and Docetaxel works better than four cycles of Pertuzumab plus Trastuzumab and Docetaxel in women with HER2-positive early- to locally advanced breast cancer.

  Recruiting Phase 3 Shanghai Jiao Tong University School of Medicine · Shanghai · NCT07797218

• Histidine supplementation to support immune function in colorectal cancer

  This study tests whether taking histidine by mouth alongside standard colorectal cancer treatment helps boost antitumor immune responses.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT07577505

• Support system to make brace wear easier for teens with scoliosis

  This project will test a combined sensor, home terminal, and mobile app system to help teenagers with adolescent idiopathic scoliosis wear their corrective brace more comfortably and consistently.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT07574229

• Early heart muscle changes to spot severe pediatric lupus

  This project will test whether non-invasive heart ultrasound measurements can help identify children with severe, treatment-resistant lupus.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT07425730

• Pre-surgery trastuzumab deruxtecan (SHR-A1811) plus pertuzumab for HER2-positive breast cancer

  This trial tests giving trastuzumab deruxtecan (SHR-A1811) with pertuzumab before surgery to see if it helps women with stage II–III HER2-positive breast cancer achieve a complete response.

  Recruiting Phase 2 Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT07393425

• CS-121 base editing of APOC3 to lower triglycerides in children and adolescents with hyperchylomicronemia

  This trial will test a one-time in vivo base editing therapy (CS-121) delivered by lipid nanoparticles to lower APOC3 and reduce triglycerides in children and adolescents aged 4–18 with severe hyperchylomicronemia.

  Recruiting Early Phase 1 Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT07371767

• Neoadjuvant sacituzumab tirumotecan plus KL-A167 for triple-negative breast cancer

  This trial will test whether giving sacituzumab tirumotecan together with KL-A167 before surgery helps people aged 18–65 with primary triple-negative breast cancer (tumor ≥2 cm, no distant spread).

  Recruiting Phase 2 Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT07371208

• Standard approach and quality system for confocal enteroscopy

  This project will test whether using confocal laser endomicroscopy during balloon enteroscopy can improve diagnosis and help set quality standards for people with suspected small-bowel disease.

  Recruiting at 8 sites Shanghai Jiao Tong University School of Medicine · Hefei, Anhui and 7 other locations · NCT07363291

• VIC-1911 with PTCy and sirolimus to prevent GVHD after haploidentical stem cell transplant in children

  This early-phase trial tests whether adding VIC-1911 to a standard GVHD prevention regimen can help children tolerate and benefit after a haploidentical stem cell transplant.

  Recruiting Phase 1 Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT07350057

• Using blood ctDNA to compare two pre-surgery HER2-positive breast cancer regimens

  We will test whether two different pre-surgery drug combinations clear tumor DNA from the blood better in people with HER2-positive early breast cancer.

  Recruiting Phase 2 Shanghai Jiao Tong University School of Medicine · Shanghai · NCT07335081

• Chiglitazar for MASH and Type 2 Diabetes

  This trial tests whether chiglitazar can help adults with MASH and type 2 diabetes when added to standard vitamins and liver-supporting therapy.

  Recruiting Phase 2 Shanghai Jiao Tong University School of Medicine · Beijing, Beijing Municipality and 16 other locations · NCT07303803

• Shanghai Adrenal Disease Cohort

  This project enrolls adults with adrenal diseases to collect clinical, imaging, and lab data and samples to see if better tests, diagnoses, and treatments can be developed.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai · NCT07191951

• Blood test using cfDNA methylation to screen for biliary tract cancers

  This study tests whether a blood test that reads cfDNA methylation can detect biliary tract cancers early in adults with or suspected of having these cancers.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT07176962

• Using ctDNA methylation to guide prognosis and monitoring in pancreatic cancer

  This project tests whether a blood test that measures ctDNA methylation can help detect and monitor pancreatic cancer in adults who are undergoing surgery or biopsy.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT07045571

• Personalized vaccine for preventing relapse in acute myeloid leukemia

  This study is testing a personalized vaccine to see if it can help prevent relapse in people with acute myeloid leukemia who are in remission but still have some cancer cells left.

  Recruiting Early Phase 1 Shanghai Jiao Tong University School of Medicine · Shanghai · NCT06980155

• Using artificial intelligence to predict ischemic cerebrovascular disease early

  This study is testing whether a new artificial intelligence tool can help doctors find patients at risk of serious strokes by looking at their health data.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT06978348

• Shenling Baizhu Granule to prevent recurrence of low-risk colorectal adenoma.

  This will test whether taking Shenling Baizhu Granules for six months after polyp removal can reduce the chance that low-risk colorectal adenomas come back in adults aged 18–70.

  Recruiting Phase 4 Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT06930157

• Evaluating LE051 for treating Duchenne Muscular Dystrophy

  This study is testing a new intravenous treatment called LE051 to see if it is safe and effective for people with Duchenne Muscular Dystrophy who can benefit from a specific type of therapy.

  Recruiting Early Phase 1 Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT06900049

• Comparing two doses of melphalan for stem cell transplantation in leukemia patients

  This study is testing whether a lower or higher dose of melphalan helps adults with leukemia or myelodysplastic syndrome have better outcomes after stem cell transplantation.

  Recruiting Phase 3 Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality and 1 other locations · NCT06829472

• Evaluation of a non-invasive blood glucose meter for diabetes management

  This study is testing a new non-invasive blood glucose meter to see if it works well for people with diabetes compared to traditional methods.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT06796322

• Using PET/CT to assess breast cancer treatment effectiveness

  This study is testing a new imaging method to see how well neoadjuvant therapy works for patients with invasive breast cancer.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai · NCT06725940

• Reduced versus standard dose post-transplant cyclophosphamide with tacrolimus and a single low-dose ATG to prevent GVHD after alternative-donor peripheral stem cell transplant

  This trial will see if a lower dose (35 mg/kg) of post-transplant cyclophosphamide plus tacrolimus and one low dose of ATG prevents graft-versus-host disease as well as the standard 50 mg/kg dose in patients receiving an allogeneic peripheral stem cell transplant from an unrelated or haploidentical donor.

  Recruiting Phase 3 Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT06705062

• Evaluating BBM-D101 for treating Duchenne Muscular Dystrophy

  This study is testing a new gene therapy called BBM-D101 to see if it can help boys aged 4 to 8 with Duchenne Muscular Dystrophy improve their muscle function and slow down the disease.

  Recruiting Early Phase 1 Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT06641895

• Evaluating Blinatumomab for Pediatric B-Lymphoblastic Leukemia

  This study is testing if a new treatment called Blinatumomab can help children with newly diagnosed acute B-Lymphoblastic leukemia who didn't respond well to their first round of chemotherapy.

  Recruiting at 2 sites Phase 2/3 Shanghai Jiao Tong University School of Medicine · Hefei, Anhui and 3 other locations · NCT06607419

• Magnetic Seizure Therapy plus antipsychotics for psychotic disorders

  This trial will test whether adding Magnetic Seizure Therapy to antipsychotic medication helps adults with acute psychotic disorders get better faster and with fewer cognitive side effects than medication alone.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality and 1 other locations · NCT06581302

• 68Ga-FAPI PET/CT for axillary lymph node status after neoadjuvant therapy in clinically node-positive breast cancer

  This will see if 68Ga-FAPI PET/CT can find residual cancer in underarm (axillary) lymph nodes after neoadjuvant treatment in people with clinically node-positive breast cancer.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT06559371

• Neoadjuvant adebrelimab plus chemotherapy for high-risk ER-positive/HER2-negative breast cancer

  This trial will test whether adding adebrelimab, an anti–PD‑L1 drug, to standard neoadjuvant chemotherapy helps people with early or locally advanced high‑risk ER‑positive/HER2‑negative breast cancer achieve a complete tumor response before surgery.

  Recruiting Phase 2 Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT06500208

• Comparing two types of stem cell transplants for children

  This study is testing whether a new type of stem cell transplant can reduce complications and improve life for children who need this treatment.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT06423131

• Investigating the effects of treating Helicobacter Pylori on dyspepsia symptoms

  This study is testing if treating Helicobacter pylori can help people with upset stomach symptoms feel better over time.

  Recruiting at 26 sites Shanghai Jiao Tong University School of Medicine · Chongqing, Chongqing Municipality and 25 other locations · NCT06422052

• Investigating the link between atrophic gastritis and gastric cancer risk

  This study is trying to see if people with atrophic gastritis are more likely to develop gastric cancer, especially in areas where gastric cancer is common.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT06203327

• Personalized mRNA vaccine for advanced endocrine tumors

  This study is testing a personalized mRNA vaccine to see if it can help patients with advanced endocrine tumors who haven't had success with standard treatments.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT06141369

• Comparing conditioning regimens for patients with acute myeloid leukemia or myelodysplastic syndromes

  This study is testing two different treatment plans for adults with acute myeloid leukemia or myelodysplastic syndromes to see which one helps prevent the disease from coming back after a stem cell transplant.

  Recruiting at 9 sites Phase 3 Shanghai Jiao Tong University School of Medicine · Fuzhou, Fujian and 8 other locations · NCT05991908

• Short-course treatment for early HER2-positive breast cancer

  This study is testing a shorter treatment plan with two medications for early HER2-positive breast cancer to see if it works just as well as the usual year-long treatment but with fewer side effects.

  Recruiting Phase 2 Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT05891561

• Combining Chidamide and Venetoclax for Hard-to-Treat Acute Promyelocytic Leukemia

  This study is testing a new combination of two drugs, chidamide and venetoclax, to see if it can help people with hard-to-treat acute promyelocytic leukemia who haven't responded to standard treatments.

  Recruiting at 2 sites Phase 2 Shanghai Jiao Tong University School of Medicine · Huai'an, Jiangsu and 4 other locations · NCT05881265

• Using doxycycline to treat Helicobacter pylori infections

  This study is testing if a new 14-day treatment using doxycycline can effectively help people with Helicobacter pylori infections who haven't responded to previous treatments.

  Recruiting Phase 4 Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT05874570

• Chemotherapy and Reduced Intensity Conditioning for Refractory Acute Myeloid Leukemia

  This study is testing a new treatment plan that combines a special chemotherapy with a gentler conditioning method to see if it helps people with hard-to-treat acute myeloid leukemia feel better and live longer.

  Recruiting at 3 sites Phase 2 Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality and 2 other locations · NCT05870995

• Observational study on autoimmune hepatitis in China

  This study looks at the experiences and long-term health of people with autoimmune hepatitis in China to see how well different treatments work and what factors affect their recovery.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT05785793

• Evaluating VGN-R09b for treating AADC deficiency

  This study is testing a new gene therapy called VGN-R09b to see if it can help people with AADC deficiency by improving their symptoms.

  Recruiting Early Phase 1 Shanghai Jiao Tong University School of Medicine · Shanghai, No. 1678, Dongfang Road, Pudong New Area, Shanghai · NCT05765981

• Registry of Obstructive Sleep Apnea in Hypertensive Patients in China

  This study looks at how well people with high blood pressure and sleep apnea stick to using a CPAP machine and how it affects their health over time.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT05735444

• Reduced intensity conditioning for older patients with myeloid malignancies

  This study is testing a gentler treatment plan for older patients with blood cancers to see if it helps them live longer and healthier after a stem cell transplant.

  Recruiting at 2 sites Phase 2 Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality and 1 other locations · NCT05436561

• Registry for Renal Artery Fibromuscular Dysplasia

  This study is creating a registry to learn more about renal artery fibromuscular dysplasia in patients in China, including what causes it and how to manage it better.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT05363748

• Comparing two treatment approaches for advanced oral squamous cell carcinoma

  This study is testing whether a new combination treatment for advanced oral cancer can work better than the standard treatment to help patients before surgery.

  Recruiting Phase 2/3 Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT05125055

• Personalized anti-PD-1 and anti-VEGFR therapy for oral cancer patients

  This study is testing a personalized treatment combining two medications for patients with advanced oral cancer to see if it helps them stay cancer-free for longer after surgery.

  Recruiting Phase 2 Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT05069857

• Diagnosis and treatment of complicated adrenal tumors

  This study is trying to find better ways to diagnose and treat people with complicated adrenal tumors by looking at different factors that affect their condition.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT04529629

• Reducing antibiotic use for patients with neutropenic fever after stem cell transplantation

  This study is testing if stopping antibiotics early is safe for patients with neutropenic fever after stem cell transplantation who have been fever-free for 72 hours.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT04270786

• Program for screening and preventing diabetic retinopathy

  This study is testing a new program that uses advanced technology to help find and manage diabetic retinopathy early in diabetes patients in China.

  Recruiting at 2 sites Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality and 1 other locations · NCT04240652

• Study on how overweight and obesity affect puberty in children

  This study looks at how being overweight or obese affects the timing of puberty in children aged 6 to 12 by tracking their growth and environment over three years.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT04113070

• Evaluation of early child development and education in Shanghai

  This study looks at how children aged 3-6 in Shanghai are developing to see how early education can be improved.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT04037761

• National Diabetes Management Program in China

  This study is trying to create a nationwide database to help improve the care and understanding of diabetes in China by collecting health information and samples from patients.

  Recruiting Shanghai Jiao Tong University School of Medicine · Multiple Locations · NCT03811470

• Using stathmin to predict chemotherapy outcomes in oral cancer

  This study is testing if measuring stathmin levels can help predict which patients with oral cancer will benefit more from a specific chemotherapy treatment.

  Recruiting Phase 2 Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT03326947

• Testing different chemotherapy drugs plus surgery for prostate cancer patients without metastasis

  This study is testing if giving different chemotherapy drugs before surgery can help men with localized prostate cancer control their tumors better and lower the chances of the cancer getting worse.

  Recruiting at 2 sites Phase 2/3 Shanghai Jiao Tong University School of Medicine · Qingdao, Shandong and 1 other locations · NCT03258320

• Testing chemotherapy options for breast cancer patients undergoing surgery

  This study is testing different chemotherapy drugs to see how well they help women with a common type of breast cancer before or after surgery.

  Recruiting at 3 sites Phase 1 Shanghai Jiao Tong University School of Medicine · Ganzhou, Jiangxi and 2 other locations · NCT02897700

• Chemotherapy combined with surgery for recurrent non-small cell lung cancer

  This study is testing different chemotherapy drugs combined with surgery to see if they can help people with recurrent non-small cell lung cancer live longer and feel better after their initial treatment.

  Recruiting at 3 sites Phase 1 Shanghai Jiao Tong University School of Medicine · Changchun, Jilin and 2 other locations · NCT02889666

• Chemotherapy for advanced oral cancer patients with high cyclin D1 expression

  This study is testing if a specific chemotherapy treatment can help people with advanced oral cancer who have high levels of a protein called cyclin D1 live longer and stay cancer-free after treatment.

  Recruiting Phase 2 Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT02290145

• Exploring genetic factors of obesity in young Chinese individuals

  This study is trying to see how genetics might play a role in obesity among young people in China by comparing those who are obese with those who are not.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT01084967

Quick answers

How many clinical trials run by Shanghai Jiao Tong University School of Medicine are recruiting right now?

60, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in China. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 12, Early Phase 1: 5, Phase 3: 4, Phase 1: 3. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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