Clinical trial Recruiting at 1 site Observational Ages 18 to 75

Diagnosis and treatment of complicated adrenal tumors

Official title: Precise Diagnosis, Treatment and Prognostic Evaluation of Complicated Adrenal Tumor Diseases

Run by Shanghai Jiao Tong University School of Medicine · NCT04529629 · Data updated 2026-11-12

This study is trying to find better ways to diagnose and treat people with complicated adrenal tumors by looking at different factors that affect their condition.

Quick facts

Study typeObservational
Ages18 Years to 75 Years
SexAll
Enrollment1000 (estimated)
SponsorShanghai Jiao Tong University School of Medicine
Academic / other
Locations1 site (Shanghai, Shanghai Municipality)
StatusRecruiting
StartedAugust 30, 2021
Main results expectedAugust 30, 2040
Study endsAugust 30, 2041
Registry record updatedDecember 27, 2021
Trial IDNCT04529629 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 to 75 diagnosed with primary aldosteronism, pheochromocytoma, or cortical cancer.

Probably not a fit

Patients with renal insufficiency, liver cirrhosis, current corticosteroid use, severe cardiac insufficiency, recent stroke or myocardial infarction, or those who are pregnant or lactating may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients with complicated adrenal tumor diseases, aiming to improve diagnosis, treatment, and prognostic evaluation. It addresses key challenges such as hormone secretion variability, limitations of traditional imaging, unclear molecular characteristics of tumors, and difficulties in pathology assessments. By analyzing these factors, the study seeks to enhance early diagnosis and precise treatment options for affected individuals. The interventions may include surgical procedures or pharmacological treatments.

Why it matters

Potential benefit: If successful, this study could lead to more accurate diagnoses and effective treatments for patients with adrenal tumors, potentially improving their prognosis.

How similar studies have gone: While there may be studies addressing adrenal tumors, this approach focuses on a comprehensive evaluation of multiple diagnostic and treatment challenges, making it a novel endeavor.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years old and ≤ 75 years
* Diagnosis of Patients with primary aldosteronism, pheochromocytoma, and cortical cancer
* Gender: males and females
* Provide written informed consent
* Satisfactory compliance

Exclusion Criteria:

1. Patients with renal insufficiency (Cr\>2 times the upper limit of normal).
2. Patients with a history of liver cirrhosis.
3. Patients who are currently using corticosteroids.
4. Patients with cardiac insufficiency (NYHA cardiac function classification grade 3 and above or EF\<50%).
5. Patients with stroke and acute myocardial infarction in the past 6 months.
6. Patients during pregnancy and lactation

Where it's running

  • Ruijin Hospital
    Shanghai, Shanghai Municipality, China
    Recruiting

Study contacts

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.