Investigating the link between atrophic gastritis and gastric cancer risk
Official title: Atrophic Gastritis Predicts the Risk of Gastric Cancer: a Prospective Cohort Study
Run by Shanghai Jiao Tong University School of Medicine · NCT06203327 · Data updated 2026-11-12
This study is trying to see if people with atrophic gastritis are more likely to develop gastric cancer, especially in areas where gastric cancer is common.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 70 Years |
| Sex | All |
| Enrollment | 2042 (estimated) |
| Sponsor | Shanghai Jiao Tong University School of Medicine Academic / other |
| Locations | 1 site (Shanghai, Shanghai Municipality) |
| Status | Recruiting |
| Started | December 15, 2023 |
| Main results expected | December 31, 2034 |
| Study ends | December 31, 2034 |
| Registry record updated | December 30, 2024 |
| Trial ID | NCT06203327 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals aged 18 to 80 who have atrophic gastritis and are willing to provide informed consent.
✕Probably not a fit
Patients with a history of gastrectomy or severe systemic diseases or malignancies may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to explore the incidence of gastric cancer (GC) associated with atrophic gastritis in a region known for high GC rates. It will involve esophagogastroscopy procedures to assess the severity of gastric mucosal atrophy and intestinal metaplasia, which are significant risk factors for developing GC. The study will collect biopsies following the updated Sydney system recommendations to ensure accurate data collection and analysis. By understanding this relationship, the study seeks to provide insights into early detection and prevention strategies for gastric cancer.
Why it matters
Potential benefit: If successful, this study could enhance early detection and prevention strategies for gastric cancer in at-risk populations.
How similar studies have gone: Previous studies have indicated a strong correlation between atrophic gastritis and gastric cancer, suggesting that this approach is supported by existing literature.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Ability and willingness to participate in the study and to sign and give informed consent * Biopsies were collected based on the recommendation of updated Sydney system Exclusion Criteria: * under 18 or over 80 years old * history of gastrectomy * severe systemic diseases or malignancy
Where it's running
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Renji Hospital, School of Medicine, Shanghai Jiao Tong University
Shanghai, Shanghai Municipality, China Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.