Clinical trial Recruiting at 1 site Observational Ages 18 to 70

Investigating the link between atrophic gastritis and gastric cancer risk

Official title: Atrophic Gastritis Predicts the Risk of Gastric Cancer: a Prospective Cohort Study

Run by Shanghai Jiao Tong University School of Medicine · NCT06203327 · Data updated 2026-11-12

This study is trying to see if people with atrophic gastritis are more likely to develop gastric cancer, especially in areas where gastric cancer is common.

More Atrophic Gastritis trials

Quick facts

Study typeObservational
Ages18 Years to 70 Years
SexAll
Enrollment2042 (estimated)
SponsorShanghai Jiao Tong University School of Medicine
Academic / other
Locations1 site (Shanghai, Shanghai Municipality)
StatusRecruiting
StartedDecember 15, 2023
Main results expectedDecember 31, 2034
Study endsDecember 31, 2034
Registry record updatedDecember 30, 2024
Trial IDNCT06203327 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are individuals aged 18 to 80 who have atrophic gastritis and are willing to provide informed consent.

Probably not a fit

Patients with a history of gastrectomy or severe systemic diseases or malignancies may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the incidence of gastric cancer (GC) associated with atrophic gastritis in a region known for high GC rates. It will involve esophagogastroscopy procedures to assess the severity of gastric mucosal atrophy and intestinal metaplasia, which are significant risk factors for developing GC. The study will collect biopsies following the updated Sydney system recommendations to ensure accurate data collection and analysis. By understanding this relationship, the study seeks to provide insights into early detection and prevention strategies for gastric cancer.

Why it matters

Potential benefit: If successful, this study could enhance early detection and prevention strategies for gastric cancer in at-risk populations.

How similar studies have gone: Previous studies have indicated a strong correlation between atrophic gastritis and gastric cancer, suggesting that this approach is supported by existing literature.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Ability and willingness to participate in the study and to sign and give informed consent
* Biopsies were collected based on the recommendation of updated Sydney system

Exclusion Criteria:

* under 18 or over 80 years old
* history of gastrectomy
* severe systemic diseases or malignancy

Where it's running

  • Renji Hospital, School of Medicine, Shanghai Jiao Tong University
    Shanghai, Shanghai Municipality, China
    Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.