Exploring genetic factors of obesity in young Chinese individuals
Official title: Study of Clinical Characteristics and Genetic Susceptibility in Chinese Obese Youngs
Run by Shanghai Jiao Tong University School of Medicine · NCT01084967 · Data updated 2026-11-12
This study is trying to see how genetics might play a role in obesity among young people in China by comparing those who are obese with those who are not.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 14 Years to 30 Years |
| Sex | All |
| Enrollment | 8000 (estimated) |
| Sponsor | Shanghai Jiao Tong University School of Medicine Academic / other |
| Locations | 1 site (Shanghai, Shanghai Municipality) |
| Status | Recruiting |
| Started | March 2009 |
| Main results expected | April 2030 |
| Study ends | April 2030 |
| Registry record updated | May 12, 2026 |
| Trial ID | NCT01084967 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals with a body mass index (BMI) of 30 kg/m2 or higher, predominantly from East China.
✕Probably not a fit
Patients with obesity caused by specific medical conditions such as Cushing syndrome or those with a history of major psychiatric illness may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to investigate the genetic susceptibility and pathogenesis of obesity among young individuals in China. By enrolling obese patients and healthy lean controls, the study will utilize advanced techniques such as enzyme-linked immunosorbent assay and real-time fluorescence quantitative PCR to analyze genetic markers and copy number variations associated with obesity. The findings are expected to enhance understanding of the genetic contributions to obesity and metabolic syndrome, potentially guiding future treatment strategies.
Why it matters
Potential benefit: If successful, this study could lead to improved prevention and treatment strategies for obesity and metabolic syndrome in affected populations.
How similar studies have gone: Previous studies have identified genetic factors associated with obesity, but this study's focus on copy number variation in a specific population is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * body mass index (BMI)≥ 30kg/m2 * predominantly east China to minimize population stratification * willing and able to provide informed consent Exclusion Criteria: * pregnancy/lactation * Cushing syndrome * Hypothyroidism * obesity caused by pituitary and hypothalamic lesions * drug related obesity * history of major psychiatric illness
Where it's running
-
Shanghai Jiao Tong University School of Medicine
Shanghai, Shanghai Municipality, China Recruiting
Study contacts
- Principal investigator: Jie Hong, MD — Shanghai Jiao Tong University School of Medicine
- Study coordinator: Guang Ning, MD.PhD
- Email: guangning@medmail.com.cn
- Phone: 86-21-64370045
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.