Clinical trial Recruiting at 1 site Observational Ages 6 to 12

Study on how overweight and obesity affect puberty in children

Official title: The Effect of Childhood Overweight and Obesity and Genetic Factors on Puberty Development: a Prospective Cohort Study

Run by Shanghai Jiao Tong University School of Medicine · NCT04113070 · Data updated 2026-11-12

This study looks at how being overweight or obese affects the timing of puberty in children aged 6 to 12 by tracking their growth and environment over three years.

Quick facts

Study typeObservational
Ages6 Years to 12 Years
SexAll
Enrollment14100 (estimated)
SponsorShanghai Jiao Tong University School of Medicine
Academic / other
Locations1 site (Shanghai, Shanghai Municipality)
StatusRecruiting
StartedOctober 11, 2019
Main results expectedOctober 1, 2026
Study endsDecember 30, 2026
Registry record updatedFebruary 5, 2020
Trial IDNCT04113070 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are primary school children aged 6 to 12 years who are overweight or obese.

Probably not a fit

Children with a history of hormone drug treatment lasting more than six months will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational cohort study aims to investigate the relationship between pediatric weight status and childhood growth environment on the development of puberty in children aged 6 to 12 years. Conducted across 40 primary schools in three cities in China, the study will involve anthropometric measurements and evaluations of various environmental factors reported by parents. Participants will be followed up over three years to assess the progression of puberty stages through clinical evaluations. The study seeks to clarify the underlying mechanisms linking obesity and precocious puberty.

Why it matters

Potential benefit: If successful, this study could provide insights into preventing precocious puberty and obesity-related complications in children.

How similar studies have gone: Previous studies have indicated a correlation between childhood obesity and puberty development, suggesting that this approach may yield valuable insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Children over 6 years old from grade 1, 2 and 3 in selected primary schools in Zhongshan, Qufu and Huhhot since 2019

Exclusion Criteria:

* Children with overweight or obesity had a history of hormone drug treatment last for 6 months

Where it's running

  • Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine
    Shanghai, Shanghai Municipality, China
    Recruiting

Study contacts

  • Principal investigator: Shijian Liu, Ph.D — Shanghai Children's Medical Center
  • Study coordinator: Shijian Liu, Ph.D
  • Email: liushijian@scmc.com.cn
  • Phone: 21-38625637

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.