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Clinical trials and research at Mount Sinai Hospital, Canada

• 22Clinical trials
• 8Countries

Newest trials

All recruiting trials (22)

• Stiff Knee After Replacement: Test Hinged Revision with Low-Dose Radiation

  This trial tests whether adding low-dose radiation to a hinged revision knee replacement helps people with arthrofibrosis after knee replacement move their knee better.

  Recruiting Mount Sinai Hospital, Canada · Los Angeles, California and 3 other locations · NCT07767097

• Optimizing Anticoagulation in Pregnancies With Mechanical Heart Valves

  This study tests whether using low molecular weight heparin with low-dose aspirin during pregnancy is as safe and effective as the standard warfarin-based approach for people with mechanical heart valves.

  Recruiting Mount Sinai Hospital, Canada · Toronto, Ontario · NCT07658989

• Recovery after stopping semaglutide: effects on weight, heart risk, and appetite

  This trial will test whether gradually lowering semaglutide instead of stopping it suddenly changes weight, heart risk markers, and appetite hormones in adults with obesity who lost at least 10% of their weight on semaglutide.

  Recruiting Phase 3 Mount Sinai Hospital, Canada · Toronto, Ontario · NCT07294950

• Time-restricted eating for adults with type 2 diabetes and overweight

  This project will test whether limiting daily eating to a shorter time window helps adults with type 2 diabetes and BMI ≥25 improve blood sugar control and preserve insulin-producing cells.

  Recruiting Mount Sinai Hospital, Canada · Toronto, Ontario · NCT07272460

• Inhaled methoxyflurane for pain during IUD insertion and endometrial biopsy.

  This trial will test whether inhaled methoxyflurane (Penthrox) reduces pain during IUD insertion or endometrial biopsy in adults aged 18–65.

  Recruiting Mount Sinai Hospital, Canada · Toronto, Ontario · NCT07046572

• T-piece versus ventilator breathing support at birth for extremely premature babies

  This will test whether using a ventilator to give precise nasal positive-pressure breaths at birth helps extremely premature infants (25–28 weeks) breathe better than the standard manual T‑piece resuscitator.

  Recruiting at 7 sites Mount Sinai Hospital, Canada · Los Angeles, California and 10 other locations · NCT06849596

• Educational videos for people newly diagnosed with sarcoma

  This project will test whether watching four short sarcoma-specific videos before the first oncology visit helps newly diagnosed adults (or their caregivers) better understand the disease and treatment options.

  Recruiting Mount Sinai Hospital, Canada · Toronto, Ontario · NCT06805773

• Early palliative care for patients with advanced sarcoma

  This study tests if adding early palliative care to standard treatment can improve the quality of life for people with advanced soft tissue sarcoma.

  Recruiting Mount Sinai Hospital, Canada · Toronto, Ontario · NCT06805669

• Evaluating antiviral treatments to prevent long-term heart issues after COVID-19

  This study is testing whether antiviral treatments like Paxlovid and Remdesivir can help prevent heart problems in adults who are hospitalized with COVID-19.

  Recruiting Phase 4 Mount Sinai Hospital, Canada · Kingston, Ontario and 3 other locations · NCT06792214

• Lower versus standard abdominal gas pressure to reduce shoulder pain after gynecologic laparoscopy

  This trial will test whether using lower gas pressure (10 mm Hg) instead of standard pressure (15 mm Hg) during benign gynecologic laparoscopic surgery reduces shoulder-tip pain afterwards.

  Recruiting Mount Sinai Hospital, Canada · Toronto, Ontario · NCT06504277

• Head-elevated mask ventilation in severely obese patients

  In adults with BMI of 40 or more undergoing surgery, this study tests whether a head-elevated position improves oxygen delivery when using a face mask during anesthesia compared with lying flat.

  Recruiting Mount Sinai Hospital, Canada · Toronto, Ontario · NCT06305273

• Analyzing genetic factors in inflammatory bowel disease across different populations

  This study is trying to find out how genes and the environment affect inflammatory bowel disease by looking at samples from people with the condition and healthy individuals.

  Recruiting Mount Sinai Hospital, Canada · Toronto, Ontario · NCT06042387

• Using antibiotics to treat delirium in older adults without clear urinary infections

  This study tests whether giving antibiotics can help older adults with delirium feel better, even if they don't have a clear urinary infection.

  Recruiting at 2 sites Mount Sinai Hospital, Canada · Chicago, Illinois and 6 other locations · NCT06004739

• Presacral nerve block to reduce pain after total laparoscopic hysterectomy.

  This trial tries a presacral nerve block with ropivacaine versus a saline sham to see if it reduces pain after total laparoscopic hysterectomy in adults.

  Recruiting Phase 2 Mount Sinai Hospital, Canada · Toronto, Ontario · NCT05953766

• Predicting brain bleeding in premature infants using echocardiography and near-infrared spectroscopy

  This study is trying to see if using special imaging techniques can help doctors find premature babies at risk of serious brain bleeding early on, so they can provide better care.

  Recruiting Mount Sinai Hospital, Canada · Calgary, Alberta and 3 other locations · NCT05708105

• Breathing support methods for preterm infants

  This study is testing whether a new breathing support method for preterm infants can help them sleep better and stay healthier compared to the standard method.

  Recruiting Mount Sinai Hospital, Canada · Toronto, Ontario · NCT05589831

• Comparing Dopamine and Norepinephrine for Low Blood Pressure in Very Preterm Infants with Sepsis

  This study is testing whether Dopamine or Norepinephrine works better to help very preterm infants with low blood pressure caused by sepsis.

  Recruiting at 20 sites Mount Sinai Hospital, Canada · Phoenix, Arizona and 21 other locations · NCT05347238

• Combining acetaminophen and ibuprofen to treat heart issues in premature infants

  This study is testing if giving premature infants both acetaminophen and ibuprofen together can help treat a heart problem called patent ductus arteriosus better than using just one of the medicines alone.

  Recruiting at 6 sites Phase 2 Mount Sinai Hospital, Canada · Newcastle, New South Wales and 8 other locations · NCT05340582

• Mobile app support for patients after colorectal surgery

  This study tests if a mobile app can help patients recover better at home after colorectal surgery and reduce the need for unexpected hospital visits.

  Recruiting Mount Sinai Hospital, Canada · Toronto, Ontario · NCT04236128

• Sustainable diet to shift gut microbes and lower ulcerative colitis activity

  This project will try a sustainable non-elemental diet in adults with mild to moderately active ulcerative colitis to change gut bacteria and reduce disease activity.

  Recruiting Mount Sinai Hospital, Canada · Toronto, Ontario · NCT04121806

• Non-surgical treatment for low rectal cancer after chemotherapy and radiation

  This study is testing if patients with low rectal cancer who respond well to chemotherapy and radiation can safely avoid surgery by being closely monitored instead.

  Recruiting Mount Sinai Hospital, Canada · Toronto, Ontario · NCT03179540

• Observational study on gestational glucose tolerance in women

  This study is looking at pregnant women in their late second trimester to see how their blood sugar levels change during pregnancy and how it might affect their health after giving birth.

  Recruiting Mount Sinai Hospital, Canada · Toronto, Ontario · NCT02583061

Quick answers

How many clinical trials run by Mount Sinai Hospital, Canada are recruiting right now?

22, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in Canada (22 trials), United States (4 trials), Ireland (2 trials), Denmark (1 trial), Israel (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 4: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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