Early palliative care for patients with advanced sarcoma
Integrating Early Palliative Care in Advanced SARcoma Patients for Enhanced QUALITY of Life: the SARQUALITY Study
This study tests if adding early palliative care to standard treatment can improve the quality of life for people with advanced soft tissue sarcoma.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 136 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Mount Sinai Hospital, Canada Academic / other |
| Locations | 1 site (Toronto, Ontario) |
| Trial ID | NCT06805669 on ClinicalTrials.gov |
What this trial studies
This study aims to determine if early involvement of palliative care alongside standard treatment can enhance the quality of life for patients diagnosed with advanced or metastatic soft tissue sarcoma. Participants will complete quality of life questionnaires before starting treatment and every six weeks for a total of 24 weeks. The study will compare outcomes between those receiving standard treatment alone and those receiving both standard treatment and early palliative care.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with histologically documented advanced sarcoma who have not received prior systemic treatment for palliative intent.
Not a fit: Patients with cognitive impairments, those requiring urgent palliative care, or those actively followed by a palliative care physician may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve the quality of life for patients with advanced sarcoma.
How similar studies have performed: Other studies have shown that early palliative care can improve quality of life in various cancer populations, suggesting a promising approach in this context.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Signed written and voluntary informed consent. * Have histologically documented advanced sarcoma, either locally advanced not amenable to curative treatment, or metastatic. * Age ≥ 18 years. * Have not received any previous systemic treatment with palliative intent for advanced sarcoma. * Performance status of 0-2 on the Eastern Cooperative Oncology Group (ECOG) performance scale. * Life expectancy \> 6 months. * Willing/able to complete questionnaires. Exclusion Criteria: * Clinical evidence of cognitive impairment that would preclude the ability to provide informed consent and complete questionnaires, at investigator´s discretion. * Patient in need of urgent home support services or symptom management through a palliative care team. * Patient is being actively followed by a palliative care physician. * Active psychiatric disorder or drug abuse. * Insufficient English literacy to complete questionnaires.
Where this trial is running
Toronto, Ontario
- Mount Sinai Hospital — Toronto, Ontario, Canada (Recruiting)
Study contacts
- Principal investigator: Albiruni R. Abdul Razak — Mount Sinai Hospital
- Study coordinator: Clinical Trials Manager
- Email: Oncology.Research@sinaihealth.ca
- Phone: 416-586-8440
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.