Observational study on gestational glucose tolerance in women
Official title: Toronto Gestational Glucose Tolerance Cohort
Run by Mount Sinai Hospital, Canada · NCT02583061 · Data updated 2026-11-12
This study is looking at pregnant women in their late second trimester to see how their blood sugar levels change during pregnancy and how it might affect their health after giving birth.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 20 Years to 60 Years |
| Sex | Women only |
| Enrollment | 350 (estimated) |
| Sponsor | Mount Sinai Hospital, Canada Academic / other |
| Locations | 1 site (Toronto, Ontario) |
| Status | Recruiting |
| Started | September 2003 |
| Main results expected | October 2029 |
| Study ends | October 2029 |
| Registry record updated | May 9, 2025 |
| Trial ID | NCT02583061 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are pregnant women in their late second trimester.
✕Probably not a fit
Patients with pre-existing diabetes before the index pregnancy will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational cohort study recruits pregnant women in their late second trimester to assess their glucose tolerance status during pregnancy. Participants represent a range of glucose tolerance, from gestational diabetes to normal levels, and are followed over several years for cardiometabolic characterization. Regular assessments include evaluations of glucose tolerance, beta-cell function, and insulin sensitivity, aiming to understand the development of type 2 diabetes and cardiovascular disease post-pregnancy.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the early indicators of type 2 diabetes and cardiovascular disease in women after pregnancy.
How similar studies have gone: Similar observational studies have shown success in understanding the long-term health impacts of gestational diabetes and glucose intolerance.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pregnant women Exclusion Criteria: * Pre-existing diabetes before the index pregnancy
Where it's running
-
Mount Sinai Hospital
Toronto, Ontario, Canada Recruiting
Study contacts
- Principal investigator: Ravi Retnakaran, MD — Mount Sinai Hospital
- Study coordinator: Ravi Retnakaran, MD
- Email: ravi.retnakaran@sinaihealth.ca
- Phone: 416-586-4800
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.