Head-elevated mask ventilation in severely obese patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares two body positions during facemask ventilation after induction of general anesthesia in adults with class III obesity. Participants will be randomized to be ventilated in a supine position or in a head-elevated position, then switched to the other position to compare ventilation parameters in both setups. The primary goal is to see if head elevation improves lung ventilation measurements and oxygenation in severely obese patients. The trial is conducted at Mount Sinai Hospital in Toronto and does not involve a drug intervention. Outcomes focus on airway performance and safety during mask ventilation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* BMI \> 40 kg/m2
* age \> 18 years
* scheduled for elective surgery under general anesthesia
* have the ability to comprehend the rationale for the study and provide consent

Exclusion Criteria:

* pregnancy,
* risk of aspiration of gastric content
* patients using glucagon-like peptide(GLP)-1 agonists
* emergency cases
* upper airway disease or airway anatomical abnormalities
* presence of major cardiovascular, respiratory, or cerebral vascular disease
* if the provider anesthesiologist indicates an awake technique to secure the airway

Where it's running

• Mount Sinai Hospital
  Toronto, Ontario, Canada Recruiting

Study contacts

• Principal investigator: Fabricio Zasso, MD — Mount Sinai Hospital
• Study coordinator: Fabricio Zasso, MD
• Email: Fabricio.Zasso@sinaihealth.ca
• Phone: 416-586-4800

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.