Sponsor or institution
Clinical trials and research at Montana State University - Bozeman
As of November 12, 2026, Find a Trial lists 56 NIH-funded research projects at this institution, with $36.2 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 56NIH research projects
NIH-funded research (newest 40 of 56)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Sex- and hormone-aware computer model of cartilage metabolism and drug effects
A scientist team will build and test a computer model that predicts how cartilage cells metabolize, produce matrix, and respond to drugs, with a focus on differences between men and women and how hormones affect these processes.
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How Staphylococcus aureus’s Hlb protein helps it evade human immune cells
Researchers are studying how a toxin in MRSA changes the bacteria’s ability to dodge human neutrophils, potentially revealing new ways to prevent or treat infections.
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Translatomic changes in aging heart: ribosome players
A study to understand how aging changes the heart at the molecular level by looking at ribosomes and initiation factors in heart cells.
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Understanding why some orthobunyaviruses hurt the brain and others don’t
Researchers are studying how certain brain-invading viruses in the California serogroup cause meningitis and brain disease, so we can learn what makes some viruses more dangerous than others.
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Lyssavirus glycoprotein fusion and receptor binding revealed at the structural level
This grant uses lyssavirus proteins to map how viral surface proteins fuse with cells and bind receptors, which helps us understand how rabies-related viruses infect hosts.
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Brucella brain infection: how it gets into the brain and how the immune system helps or hinders
A mouse study is testing how Brucella bacteria reach the brain and how immune signals and T cells affect brain infection and inflammation.
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Trauma, stress, and heart health in an American Indian community
This NIH grant aims to understand how trauma affects heart and mental health among American Indian adults in Montana.
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Metabolomic biomarker profiles for osteoarthritis
A research project at Montana State University looks for metabolite patterns in blood and joint fluid that could signal early osteoarthritis before symptoms become severe.
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Data Science Core to power Montana biomedical research
A Montana program is funding a Data Science Core to help local researchers access cloud computing, big data tools, and AI methods to analyze biomedical information.
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Community Engagement Core for Montana health research networks
A program hub that connects Montana researchers, tribal health groups, and community partners to share findings, train researchers, and community members in health-related research and CBPR.
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Developmental Research Support for Montana Students and Researchers
A grant to grow biomedical research capacity in Montana by mentoring junior scientists and building networks and pipelines for students and researchers.
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Administrative Core for Montana INBRE Biomedical Collaboration
This grant funds an Administrative Core to connect Montana institutions, manage resources, and support ethical, collaborative biomedical research across the state.
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MT INBRE: A Multidisciplinary Research Network
A nationwide Montana program connects universities and health partners to share findings and boost community-based health research, with a focus on cancers and American Indian health.
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Sleep and positive feelings inprete children: pre-adolescents
Aims to understand how sleep patterns in 8–12 year-olds affect mood and motivation, using real-life sleep data, brain measures, and playful tasks.
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Phage-driven gene swapping in the Lyme disease bacterium
Aims to understand how a virus that infects Borrelia burgdorferi can move genes between strains, which could affect how Lyme disease behaves.
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Next-generation physiology tools for human gut microbiome research
Researchers are developing cutting-edge, single-cell methods to study how gut microbes function in their natural, in-body environment to better understand gut health and disease.
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How gut bacteria handle iron from heme in your digestion
This grant studies how friendly gut bacteria use iron from your diet and how that affects your iron levels and health.
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How bacteria sense invading viruses and defend themselves
Scientists are figuring out how bacteria spot viral proteins and turn on defenses, which could help fight antibiotic-resistant infections.
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Improving How Cross-Coupling Reactions Build Drug-Like Molecules
This grant aims to make palladium-catalyzed cross-coupling reactions more selective so medicinal chemists can efficiently make drug-like molecules.
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How gut bacteria help remove arsenic from the body
Researchers are looking at whether gut microbes and common antibiotics change how the body handles arsenic after people ingest it.
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Nen ?nkUmbi/EdaHiYedo Plus (NE+): improving health for American Indian youth
This program offers culturally grounded support for American Indian adolescents (ages 12–18) and their caregivers to reduce sexual risk, substance use, and mental health problems.
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Molecular sensors to detect Alzheimer-related chemical changes early
This project builds glowing protein-based sensors that reveal early chemical signals linked to Alzheimer’s disease so patients and doctors might notice changes sooner.
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Investigating how a virus affects Lyme disease bacteria
This study is looking at how a specific virus helps Lyme disease bacteria share genes, which could make them stronger and help them spread, and it's for anyone interested in understanding more about how Lyme disease is passed from animals to humans.
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How Sleep Affects Mood and Social Skills in Pre-Teens
This project looks at how sleep patterns in children aged 8-12 affect their mood and social interactions, aiming to understand how sleep influences their emotional well-being.
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Understanding how immune cells interact in brucellosis
This study is looking at how certain immune cells called B cells and T cells work together in people with brucellosis, a bacterial infection that can cause long-lasting symptoms, to find out why some patients don’t get better even after treatment, with the hope of discovering new ways to improve vaccines and treatments
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Metabolite biomarkers to spot and classify osteoarthritis early
Looks at whether patterns of small molecules in joint fluid and blood can spot and classify osteoarthritis earlier in people with joint pain.
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Understanding how bacteria that cause Lyme disease share genes
This work explores how a virus living inside the Lyme disease bacteria helps them swap genetic material, which might explain how the bacteria survive and reinfect people.
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New Ways to Understand Your Gut Microbes
This project aims to develop advanced techniques to closely observe the individual living organisms in your gut and understand how they function.
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How trauma affects heart and metabolic health in the Blackfeet community
This project looks at how childhood and historical trauma relate to heart disease risk and mental health in American Indian adults from the Blackfeet community.
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Understanding how bacteria defend against viruses and antibiotic resistance
This study is looking at how bacteria fight off viruses and how their immune systems recognize these viral invaders, which could help us understand more about antibiotic resistance and improve our knowledge of the tiny organisms living in and around us.
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Understanding enzymes that play a key role in biological processes.
This study is looking at special enzymes that help make antibiotics and fix DNA, with the hope that understanding how they work can lead to better treatments for conditions like Alzheimer's disease.
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Testing a culturally adapted treatment for substance use disorders in American Indian communities
This study is working to help American Indians at the Fort Peck Indian Reservation who are dealing with substance use issues by testing a special program designed just for their community, with local members leading the way to make sure it fits their needs.
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How gut bacteria process iron and heme
This study is looking at how certain bacteria in your gut help break down iron from food, which could help us understand more about iron deficiency and related health problems.
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Improving brain imaging with advanced fluorescent probes
This study is all about making a special imaging tool better so scientists can see how brain cells work together, and it’s designed to help researchers who are studying the brain.
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Developing sensors to detect diseases early
This study is working on new colorful dyes and proteins that can help doctors spot signs of diseases like Alzheimer's more quickly, so they can diagnose and manage patients better.
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Understanding how CRISPR systems in bacteria and archaea respond to invading RNA
This study is looking at how a special immune system in bacteria and archaea uses CRISPR to recognize and fight off invading RNA, which could help us understand how these tiny organisms protect themselves from viruses and other genetic dangers.
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Exploring how social connections affect health in the Blackfeet community
This study is looking at how having strong social connections affects the health of American Indians living on the Blackfeet reservation in Montana, and it’s for adults in that community who want to help understand and improve their health, especially regarding issues like diabetes and depression.
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How sleep affects emotions and behavior in pre-adolescents
This study is looking at how different sleep habits, especially when kids stay up late on weekends, affect the feelings and behavior of children aged 8 to 12, helping us understand how better sleep can lead to happier and healthier kids.
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Understanding how gene silencing is controlled during development
This study is looking at how certain proteins help turn off genes in cells, which is important for cells to become specialized, and it's designed for anyone interested in understanding how these processes might relate to developmental disorders and cancers.
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Improving health research for American Indian and rural communities
This study is looking at how diet, lifestyle, and mental health affect the well-being of Indigenous and rural communities in Montana, and it aims to find ways to improve health for everyone by using research that respects and understands their unique cultures.
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